Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, S Brealey, S Chick, A Keding… - Clinical …, 2021 - journals.sagepub.com
Background/Aims: There is growing interest in the use of adaptive designs to improve the
efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential …

Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, S Brealey, S Chick, A Keding, B Corbacho… - CLINICAL TRIALS, 2021 - iris.univr.it
Background/Aims: There is growing interest in the use of adaptive designs to improve the
efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential …

[PDF][PDF] Cost-effective clinical trial design: application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, SD Brealey, S Chick, A Keding, BC Martín… - Clinical trials, 2021 - pure.york.ac.uk
Abstract Background/Aims: There is growing interest in the use of adaptive designs to
improve the efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a …

Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, S Brealey, S Chick… - Clinical trials …, 2021 - pubmed.ncbi.nlm.nih.gov
Background/aims There is growing interest in the use of adaptive designs to improve the
efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential …

Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, S Brealey, S Chick, A Keding… - CLINICAL …, 2021 - cris.unibo.it
Background/Aims: There is growing interest in the use of adaptive designs to improve the
efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential …

[HTML][HTML] Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, S Brealey, S Chick, A Keding… - Clinical Trials …, 2021 - ncbi.nlm.nih.gov
Methods: Using parameter values estimated from the ProFHER pragmatic trial, including the
costs of carrying out the trial, we establish when the trial could have stopped, had the …

Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial.

M Forster, S Brealey, S Chick, A Keding… - Clinical Trials …, 2021 - europepmc.org
Methods Using parameter values estimated from the ProFHER pragmatic trial, including the
costs of carrying out the trial, we establish when the trial could have stopped, had the …

Cost-Effective Clinical Trial Design: Application of a Bayesian Sequential Stopping Rule to the ProFHER Pragmatic Trial

M Forster, S Brealey, S Chick, A Keding, B Corbacho… - 2019 - ideas.repec.org
We investigate value-based clinical trial design by applying a Bayesian decisiontheoretic
model of a sequential experiment to data from the ProFHER pragmatic trial. In the first …

Cost-Effective Clinical Trial Design: Application of a Bayesian Sequential Stopping Rule to the ProFHER Pragmatic Trial

M Forster, S Brealey, S Chick, A Keding, B Corbacho… - 2019 - econpapers.repec.org
We investigate value-based clinical trial design by applying a Bayesian decisiontheoretic
model of a sequential experiment to data from the ProFHER pragmatic trial. In the first …

[PDF][PDF] Cost-effective clinical trial design: application of a Bayesian sequential model to the ProFHER pragmatic trial

M Forster, SD Brealey, S Chick, A Keding… - Clinical …, 2021 - eprints.whiterose.ac.uk
Abstract Background/Aims: There is growing interest in the use of adaptive designs to
improve the efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a …