Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa… - Proceedings of the …, 2021 - National Acad Sciences
Affinity maturation depends on how efficiently germinal centers (GCs) positively select B
cells in the light zone (LZ). Positively selected GC B cells recirculate between LZs and dark …

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa… - … of the National …, 2021 - researchonline.lshtm.ac.uk
Affinity maturation depends on how efficiently germinal centers (GCs) positively select B
cells in the light zone (LZ). Positively selected GC B cells recirculate between LZs and dark …

[PDF][PDF] Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawaa, A Toboso-Navasaa, M Schipsb… - PNAS, 2021 - researchgate.net
Results Identification and Flow Cytometric Delineation of Positively Selected cMyc+ GC B
Cell Subpopulations. To investigate the heterogeneity of cMyc+ GC B cell compartment, we …

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa, M Schips… - Proceedings of the …, 2021 - hero.epa.gov
Affinity maturation depends on how efficiently germinal centers (GCs) positively select B
cells in the light zone (LZ). Positively selected GC B cells recirculate between LZs and dark …

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa… - Proceedings of the …, 2021 - pubmed.ncbi.nlm.nih.gov
Affinity maturation depends on how efficiently germinal centers (GCs) positively select B
cells in the light zone (LZ). Positively selected GC B cells recirculate between LZs and dark …

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa, M Schips… - Proceedings of the …, 2021 - JSTOR
Affinity maturation depends on how efficiently germinal centers (GCs) positively select B
cells in the light zone (LZ). Positively selected GC B cells recirculate between LZs and dark …

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth.

R Nakagawa, A Toboso-Navasa, M Schips, G Young… - 2021 - repository.helmholtz-hzi.de
Affinity maturation depends on how efficiently germinal centers (GCs) positively select B
cells in the light zone (LZ). Positively selected GC B cells recirculate between LZs and dark …

[PDF][PDF] Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawaa, A Toboso-Navasaa, M Schipsb… - PNAS, 2021 - crick.figshare.com
Results Identification and Flow Cytometric Delineation of Positively Selected cMyc+ GC B
Cell Subpopulations. To investigate the heterogeneity of cMyc+ GC B cell compartment, we …

[HTML][HTML] Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa, M Schips… - Proceedings of the …, 2021 - ncbi.nlm.nih.gov
Results Identification and Flow Cytometric Delineation of Positively Selected cMyc+ GC B
Cell Subpopulations. To investigate the heterogeneity of cMyc+ GC B cell compartment, we …

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

R Nakagawa, A Toboso-Navasa… - Proceedings of the …, 2021 - ui.adsabs.harvard.edu
Light zone (LZ) B cells are selected in germinal centers (GCs) in a cMyc-dependent manner,
before dark zone (DZ) migration. Antigen affinity of B cells is enhanced during GC …