[PDF][PDF] The GSK3-NRF2 Axis in Suicide. Psychiatry Int. 2021, 2, 108–119

HO Kalkman - 2021 - pdfs.semanticscholar.org
Mutations in the genes coding for tryptophan-hydrolase-2 and the scaffold protein FKBP5
are associated with an increased risk of suicide. The mutation in both cases enhances the …

[HTML][HTML] The GSK3-NRF2 axis in suicide

HO Kalkman - Psychiatry International, 2021 - mdpi.com
Mutations in the genes coding for tryptophan-hydrolase-2 and the scaffold protein FKBP5
are associated with an increased risk of suicide. The mutation in both cases enhances the …

Understanding suicide: Focusing on its mechanisms through a lithium lens

GS Malhi, P Das, T Outhred, L Irwin, G Morris… - Journal of affective …, 2018 - Elsevier
Background Current intervention strategies have been slow in reducing suicide rates,
particularly in mood disorders. Thus, for intervention and prevention, a new approach is …

[HTML][HTML] Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits

E Beurel, RS Jope - Translational psychiatry, 2014 - nature.com
Suicide is one of the leading causes of death in the United States, yet it remains difficult to
understand the mechanistic provocations and to intervene therapeutically. Stress is …

Association between FKBP5 and CRHR1 genes with suicidal behavior: A systematic review

E De la Cruz-Cano - Behavioural brain research, 2017 - Elsevier
Suicide is one of the leading causes of death around the world with approximately one
million suicides per year. An increasing number of neurobiological studies implicate HPA …

A network meta-analysis of stress mediators in suicide behaviour

N Thomas, CW Armstrong, AR Hudaib… - Frontiers in …, 2021 - Elsevier
Stress homeostatic mediators are the most consistently anomalous biomarkers observed in
suicide and may therefore point to a common 'core biology'of stress susceptibility, and …

Cracking the bell jar

K Brennand - Science Translational Medicine, 2015 - science.org
Cracking the bell jar | Science Translational Medicine news careers commentary Journals
Science Science brought to you byGoogle Indexer Log in journal-menu-img science journal-menu-img …

[HTML][HTML] Catalytic reaction model of suicide

P McPherson, S Sall, A Santos, W Thompson… - Frontiers in …, 2022 - frontiersin.org
Suicide is a devastating outcome of unresolved issues that affect mental health, general
wellbeing and socioeconomic stress. The biology of suicidal behavior is still poorly …

[HTML][HTML] Neurobiological basis of increased risk for suicidal behaviour

A Wisłowska-Stanek, K Kołosowska, P Maciejak - Cells, 2021 - mdpi.com
According to the World Health Organization (WHO), more than 700,000 people die per year
due to suicide. Suicide risk factors include a previous suicide attempt and psychiatric …

Mood stabilizers, glycogen synthase kinase-3β and cell survival

RS Jope, GN Bijur - Molecular Psychiatry, 2002 - nature.com
Glycogen synthase kinase-3β (GSK3β) is a central figure in many intracellular signaling
systems and is directly regulated by lithium. Substantial evidence now indicates that an …