The hypothalamic-pituitary-adrenal (HPA) axis is involved in the pathophysiology of many
neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic …

Accumulating evidence indicates that patients with severe mental disorders, including major
depression, bipolar disorder and schizophrenia present with various alterations of the gut …

The aim of this article is to summarize the pathways connecting the gut and the brain and to
highlight their role in the development of depression as well as their potential use as …

Background: One of the most enduring and replicated findings in biological psychiatry is
activation of the hypothalamic-pituitary-adrenal (HPA) axis in a subset of patients with major …

According to the corticoid receptor hypothesis of depression, hyperactivity of the
hypothalamic–pituitary–adrenocortical (HPA) system is one of the major pathophysiological …

Major depressive disorder (MDD) is a very common stress-related mental disorder that
carries a huge burden for affected patients and the society. It is associated with a high …

Mood disorders rank among the leading causes of disability worldwide, and are
characterized by biological, emotional, psychological and cognitive symptoms. The …

The role of gut microbiota and its association with the central nervous system via the
microbiome-brain-gut axis has been widely discussed in the literature. The aim of this review …

The human gut microbiota plays a significant role in the pathophysiology of central nervous
system-related diseases. Recent studies suggest correlations between the altered gut …

The importance of interactions between the brain and the gastrointestinal tract has been
increasingly recognized in recent years. It has been proposed that dysregulation and …