A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …
[HTML][HTML] Phenotypic variation of transcriptomic cell types in mouse motor cortex
Cortical neurons exhibit extreme diversity in gene expression as well as in morphological
and electrophysiological properties 1, 2. Most existing neural taxonomies are based on …
and electrophysiological properties 1, 2. Most existing neural taxonomies are based on …
[HTML][HTML] Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH
A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
Comparative cellular analysis of motor cortex in human, marmoset and mouse
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals. Here, using high-throughput transcriptomic and epigenomic …
conserved across mammals. Here, using high-throughput transcriptomic and epigenomic …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
Genetic and epigenetic mechanisms contribute to motor neuron pathfinding
K Sharma, AE Leonard, K Lettieri, SL Pfaff - Nature, 2000 - nature.com
Many lines of evidence indicate that genetically distinct subtypes of motor neurons are
specified during development, with each type having characteristic properties of axon …
specified during development, with each type having characteristic properties of axon …
Brain-wide correspondence of neuronal epigenomics and distant projections
Single-cell analyses parse the brain's billions of neurons into thousands of 'cell-type'clusters
residing in different brain structures. Many cell types mediate their functions through targeted …
residing in different brain structures. Many cell types mediate their functions through targeted …
Molecularly defined and spatially resolved cell atlas of the whole mouse brain
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …
a wide range of functions. The enormous diversity and intricate organization of cells have …
Epigenomic diversity of cortical projection neurons in the mouse brain
Neuronal cell types are classically defined by their molecular properties, anatomy and
functions. Although recent advances in single-cell genomics have led to high-resolution …
functions. Although recent advances in single-cell genomics have led to high-resolution …