Neuroinflammation: a signature or a cause of epilepsy?

E Pracucci, V Pillai, D Lamers, R Parra… - International journal of …, 2021 - mdpi.com
Epilepsy can be both a primary pathology and a secondary effect of many neurological
conditions. Many papers show that neuroinflammation is a product of epilepsy, and that in …

The role of inflammation in the development of epilepsy

A Rana, AE Musto - Journal of neuroinflammation, 2018 - Springer
Epilepsy, a neurological disease characterized by recurrent seizures, is often associated
with a history of previous lesions in the nervous system. Impaired regulation of the activation …

The role of inflammation in epilepsy

A Vezzani, J French, T Bartfai, TZ Baram - Nature reviews neurology, 2011 - nature.com
Epilepsy is the third most common chronic brain disorder, and is characterized by an
enduring predisposition to generate seizures. Despite progress in pharmacological and …

Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy

YN Paudel, MF Shaikh, S Shah, Y Kumari… - European journal of …, 2018 - Elsevier
Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover,
the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities …

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

A Vezzani, S Balosso, T Ravizza - Nature Reviews Neurology, 2019 - nature.com
Epilepsy is a chronic neurological disease characterized by an enduring propensity for
generation of seizures. The pathogenic processes of seizure generation and recurrence are …

[HTML][HTML] Inflammatory and immune mechanisms underlying epileptogenesis and epilepsy: From pathogenesis to treatment target

I Mukhtar - Seizure, 2020 - Elsevier
Epilepsy is a brain disease associated with epileptic seizures as well as with
neurobehavioral outcomes of this condition. In the last century, inflammation emerged as a …

Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies

W Li, J Wu, Y Zeng, W Zheng - Frontiers in Immunology, 2023 - frontiersin.org
Epilepsy is a group of enduring neurological disorder characterized by spontaneous and
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …

Neuroinflammatory mediators in acquired epilepsy: an update

Y Chen, MM Nagib, N Yasmen, MN Sluter… - Inflammation …, 2023 - Springer
Epilepsy is a group of chronic neurological disorders that have diverse etiologies but are
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …

Inflammation and epilepsy: preclinical findings and potential clinical translation

G Terrone, A Salamone… - Current pharmaceutical …, 2017 - ingentaconnect.com
Background: The lack of treatments which can prevent epilepsy development or improve
disease prognosis represents an unmet and urgent clinical need. The development of such …

Reactive glia inflammatory signaling pathways and epilepsy

P Sanz, MA Garcia-Gimeno - International journal of molecular sciences, 2020 - mdpi.com
Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …