[HTML][HTML] When less is more: reevaluating the role of intensive chemotherapy for older adults with acute myeloid leukemia in the modern era

NJ Short, H Kantarjian - Journal of Clinical Oncology, 2021 - ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is predominantly a disease of older age, with a median age
of 68 years at diagnosis. 1 Older and unfit adults with AML (herein defined as age $60 …

Treating acute myeloid leukemia in older adults

ES Wang - Hematology 2014, the American Society of …, 2014 - ashpublications.org
Acute myeloid leukemia (AML) is a disease of older adults, with a median age of 67 years at
presentation. In the past, only a third of older patients (defined as individuals older than 60 …

[PDF][PDF] Acute myeloid leukemia in older patients: conventional and new therapies

S Amadori, M Breccia, R Stasi - Haematologica, 2013 - library.ehaweb.org
Introduction Acute myeloid leukemia (AML), a disease affecting primarily older adults with a
median age at presentation of approximately 68 years, continues to pose significant …

Advances and unanswered questions in management of acute myeloid leukemia in older adults: a glimpse into the future

VR Bhatt - Journal of geriatric oncology, 2021 - Elsevier
Advances in molecular diagnostics and drug development have ushered an era of precision
oncology in acute myeloid leukemia (AML). The availability of effective molecularly targeted …

Treatment of elderly acute myeloid leukemia patients

G Motyckova, RM Stone - Current treatment options in oncology, 2011 - Springer
Opinion statement Older patients with acute myelogenous leukemia (AML) fare much less
well than younger patients with the same disease due to a combination of comorbidities and …

Patterns of care and survival for elderly acute myeloid leukemia—challenges and opportunities

AA Mangaonkar, MM Patnaik - Current Hematologic Malignancy Reports, 2017 - Springer
Abstract Purpose of Review Acute myeloid leukemia (AML) is a disease of the elderly, with a
median age of diagnosis in the sixth decade of life. Mortality has declined over the last few …

Evolution of Therapy for Older Patients With Acute Myeloid Leukemia: How Should We Use Currently Available Agents?

TM Kadia, AH Wei - The Cancer Journal, 2022 - journals.lww.com
Most patients with newly diagnosed acute myeloid leukemia (AML) are 65 years or older.
The treatment of AML in older patients has been characterized by distinct patient-and …

Non-intensive acute myeloid leukemia therapies for older patients

R Babakhanlou, F Ravandi-Kashani - Expert review of hematology, 2023 - Taylor & Francis
Introduction Acute myeloid leukemia (AML) is an aggressive disease predominantly
affecting the elderly population. The elderly population represents a challenging group to …

Recent developments in the treatment of older individuals with acute myeloid leukemia: 2014

LC Michaelis, HP Erba - Current opinion in hematology, 2015 - journals.lww.com
Although anthracycline and cytarabine-based therapy remains the standard of care for older
patients with AML, this option remains suboptimal for the vast majority of patients. We argue …

Emerging treatment strategies for acute myeloid leukemia (AML) in the elderly

A Kuendgen, U Germing - Cancer Treatment Reviews, 2009 - Elsevier
Acute myeloid leukemia (AML) is more prevalent in older adults, with an incidence in the
United States of 17.6 per 100,000 for those⩾ 65 years of age, compared with an incidence of …