Co-assembly of block copolymer thin films and signalling molecules for stimuli-responsive biointerface

I Monteiro - 2021 - researchspace.auckland.ac.nz
The ability of stem cells to either self-renew or differentiate towards other cell types is tightly
regulated in space and time by the cell microenvironment and interactions between the cell …

Polymer-Protein Hybrid Thin Films through Co-Assembly: Optimisation, Characterisation, Functionalisation

T Kollmetz - 2021 - researchspace.auckland.ac.nz
Stem cells have the remarkable ability to self-renew and differentiate into other cell types.
The cell fate is regulated precisely by the cell's microenvironment and the interaction of the …

Multilayer films assembled from naturally-derived materials for controlled protein release

BB Hsu, SR Hagerman, K Jamieson… - …, 2014 - ACS Publications
Herein we designed and characterized films composed of naturally derived materials for
controlled release of proteins. Traditional drug delivery strategies rely on synthetic or …

Growth factor-bearing polymer brushes-versatile bioactive substrates influencing cell response

E Psarra, E Foster, U König, J You, Y Ueda… - …, 2015 - ACS Publications
In this study we present the development of responsive nanoscale substrates exhibiting cell-
guiding properties based on incorporated bioactive signaling cues. The investigative …

Development of Egnineered Biointerfaces for the Incorporation and Release of Bioactive Molecules

MS Horrocks - 2023 - researchspace.auckland.ac.nz
This thesis aims to contribute to and deepen the arsenal of synthetic extracellular matrix
(ECM) mimetic substrates for in vitro cell research. Particularly, this thesis focuses on …

Self-assembly of poly (ethylene glycol)-based block copolymers for biomedical applications

H Otsuka, Y Nagasaki, K Kataoka - Current Opinion in Colloid & Interface …, 2001 - Elsevier
Nanostructure fabrication from block copolymers is discussed in this review paper.
Particularly, novel approaches for the construction of functionalized poly (ethylene …

Quantitative analysis of biomolecule release from polystyrene-block-polyethylene oxide thin films

MS Horrocks, T Kollmetz, P O'Reilly, D Nowak… - Soft Matter, 2022 - pubs.rsc.org
Block copolymers have garnered recent attention due to their ability to contain molecular
cargo within nanoscale domains and release said cargo in aqueous environments …

Nanopatterning biomolecules by block copolymer self-assembly

KL Killops, N Gupta, MD Dimitriou, NA Lynd… - ACS Macro …, 2012 - ACS Publications
The fabrication of sub-100 nm features with bioactive molecules is a laborious and
expensive process. To overcome these limitations, we present a modular strategy to create …

Nanofabrication on Reactive Block Copolymer Film Platforms: Toward Microdomain-Selective Chemical Functionalization

C Feng, X Dou, Y Xu, C Feng, X Dou, Y Xu - Microfabrication of Stimuli …, 2021 - Springer
In this chapter, the surfaces of polystyrene-b-poly (t-butyl acrylate)(PS 690-b-PtBA 1210)
ultrathin films were restructured using cyclohexane as selective solvent. As revealed by AFM …

Polystyrene-block-poly(ethylene oxide) Thin Films Fabricated from a Solvent Mixture for the Co-Assembly of Polymers and Proteins

T Kollmetz, I Monteiro A, JA Gerrard, J Malmström - ACS omega, 2020 - ACS Publications
The co-assembly of peptides and proteins in poly (styrene-block-ethylene oxide)(PS-b-PEO)
thin films has proven to be a promising method to fabricate polymer–biomolecule functional …