Recent advances in biomaterial scaffolds for integrative tumor therapy and bone regeneration

Z Huang, Z Tian, M Zhu, C Wu, Y Zhu - Advanced Therapeutics, 2021 - Wiley Online Library
Bone tumors bring great pain to patients, along with a high disability rate and high mortality.
Several therapeutic strategies have been applied to treat bone tumors, such as …

Biomaterial-based strategy for bone tumor therapy and bone defect regeneration: An innovative application option

Y Zhang, Y Wu, X Qiao, T Lin, Y Wang… - Frontiers in Materials, 2022 - frontiersin.org
Bone tumors are deadly and incurable diseases that invade large areas of bone, resulting in
bone defects. Traditional therapies combining surgery, chemotherapy, and radiation have …

[HTML][HTML] Bifunctional scaffolds for tumor therapy and bone regeneration: Synergistic effect and interplay between therapeutic agents and scaffold materials

J Yuan, Z Ye, Y Zeng, Z Pan, ZZ Feng, Y Bao, Y Li… - Materials Today Bio, 2022 - Elsevier
Bone tumor patients often face the problems with cancer cell residues and bone defects after
the operation. Therefore, researchers have developed many bifunctional scaffolds with both …

Functional anti-bone tumor biomaterial scaffold: construction and application

B Huang, Z Yin, F Zhou, J Su - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Bone tumors, including primary bone tumors and bone metastases, have been plagued by
poor prognosis for decades. Although most tumor tissue is removed, clinicians are still …

Review of a new bone tumor therapy strategy based on bifunctional biomaterials

J Liao, R Han, Y Wu, Z Qian - Bone research, 2021 - nature.com
Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

Innovative Biomaterials for Bone Tumor Treatment and Regeneration: Tackling Postoperative Challenges and Charting the Path Forward

Y Wang, H Zhang, H Qiang, M Li, Y Cai… - Advanced …, 2024 - Wiley Online Library
Surgical resection of bone tumors is the primary approach employed in the treatment of
bone cancer. Simultaneously, perioperative interventions, particularly postoperative …

Progress of biomaterials for bone tumor therapy

H Chen, Y Yao - Journal of Biomaterials Applications, 2022 - journals.sagepub.com
Bone tumors are currently a major clinical challenge. In recent decades, strategies using
well-designed versatile biomaterials for the treatment of bone tumors have emerged and …

Using scaffolds as drug delivery systems to treat bone tumor

C Wang, Z Ma, K Yuan, T Ji - Nanotechnology, 2022 - iopscience.iop.org
Surgery is the principal strategy to treat osteosarcoma and other types of bone tumors, but it
causes bone defects that cannot be healed spontaneously. After surgery, patients still need …

Design strategies for composite matrix and multifunctional polymeric scaffolds with enhanced bioactivity for bone tissue engineering

S Kumari, S Katiyar, Darshna, A Anand, D Singh… - Frontiers in …, 2022 - frontiersin.org
Over the past few decades, various bioactive material-based scaffolds were investigated
and researchers across the globe are actively involved in establishing a potential state-of …

A review of the application of natural and synthetic scaffolds in bone regeneration

SK Wong, MMF Yee, KY Chin… - Journal of Functional …, 2023 - mdpi.com
The management of bone defects is complicated by the presence of clinical conditions, such
as critical-sized defects created by high-energy trauma, tumour resection, infection, and …