Enzymatic metabolism of flavonoids by gut microbiota and its impact on gastrointestinal cancer

RK Al-Ishaq, A Liskova, P Kubatka, D Büsselberg - Cancers, 2021 - mdpi.com
Simple Summary Flavonoid's consumption is reported to impact GI cancer progression
positively. As 90% of flavonoids consumed, undergo metabolism and conversion by the …

[HTML][HTML] The effects and mechanisms of flavonoids on cancer prevention and therapy: focus on gut microbiota

M Wang, F Yu, Y Zhang, W Chang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Flavonoids are a group of polyphenolic compounds which are ubiquitously found in plants
and are consumed as part of the human diet in substantial amounts. The verification of …

Dietary flavonoids–microbiota crosstalk in intestinal inflammation and carcinogenesis

L Wang, M Li, Y Gu, J Shi, J Yan, X Wang, B Li… - The Journal of …, 2023 - Elsevier
Colorectal cancer (CRC) is currently the third leading cancer and commonly develops from
chronic intestinal inflammation. A strong association was found between gut microbiota and …

Flavonoids and colorectal cancer prevention

Y Li, T Zhang, GY Chen - Antioxidants, 2018 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer, but despite advances in
treatment, it remains the second most common cause of cancer-related mortality. Prevention …

Flavonoid metabolism: The interaction of metabolites and gut microbiota

K Murota, Y Nakamura, M Uehara - Bioscience, biotechnology …, 2018 - academic.oup.com
Several dietary flavonoids exhibit anti-oxidative, anti-inflammatory, and anti-osteoporotic
activities relevant to prevention of chronic diseases, including lifestyle-related diseases …

The interaction between flavonoids and intestinal microbes: A review

HH Xiong, SY Lin, LL Chen, KH Ouyang, WJ Wang - Foods, 2023 - mdpi.com
In recent years, research on the interaction between flavonoids and intestinal microbes have
prompted a rash of food science, nutriology and biomedicine, complying with future research …

Where do health benefits of flavonoids come from? Insights from flavonoid targets and their evolutionary history

MF Lu, ZT Xiao, HY Zhang - Biochemical and biophysical research …, 2013 - Elsevier
Flavonoid intake is negatively correlated with the incidence of some chronic diseases
including cardiovascular diseases, type II diabetes, neurodegenerative diseases, and …

Special Issue “flavonoids and their disease prevention and treatment potential”: Recent advances and future perspectives

HPV Rupasinghe - Molecules, 2020 - mdpi.com
In recent years, the interest in flavonoids as dietary bioactives to prevent human diseases,
as well as their candidacy as pharmaceutical leads, has exponentially expanded …

Screening of human gut bacterial culture collection identifies species that biotransform quercetin into metabolites with anticancer properties

R Sankaranarayanan, PK Sekhon, A Ambat… - International journal of …, 2021 - mdpi.com
We previously demonstrated that flavonoid metabolites inhibit cancer cell proliferation
through both CDK-dependent and-independent mechanisms. The existing evidence …

Dietary flavonoids and gut microbiota interaction: A focus on animal and human studies to maximize their health benefits

L Yang, Y Gao, MA Farag, J Gong, Q Su, H Cao… - Food …, 2023 - Wiley Online Library
Flavonoids are phytochemicals that widely exist in plants, fruits, and vegetables and have a
variety of activities. However, due to their complex structure, it is often rarely absorbed into …