Chemically and biologically engineered bacteria‐based delivery systems for emerging diagnosis and advanced therapy

Z Li, Y Wang, J Liu, P Rawding, J Bu… - Advanced …, 2021 - Wiley Online Library
Bacteria are one of the main groups of organisms, which dynamically and closely participate
in human health and disease development. With the integration of chemical biotechnology …

Genetically engineered bacteria: a new frontier in targeted drug delivery

S Fooladi, N Rabiee, S Iravani - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Genetically engineered bacteria (GEB) have shown significant promises to revolutionize
modern medicine. These engineered bacteria with unique properties such as enhanced …

Engineered microbial systems for advanced drug delivery

H Shen, N Aggarwal, KS Wun, YS Lee… - Advanced Drug Delivery …, 2022 - Elsevier
The human body is a natural habitat for a multitude of microorganisms, with bacteria being
the major constituent of the microbiota. These bacteria colonize discrete anatomical …

Bioengineered and biohybrid bacteria-based systems for drug delivery

Z Hosseinidoust, B Mostaghaci, O Yasa… - Advanced drug delivery …, 2016 - Elsevier
The use of bacterial cells as agents of medical therapy has a long history. Research that was
ignited over a century ago with the accidental infection of cancer patients has matured into a …

Bacterial-based cancer therapy: An emerging toolbox for targeted drug/gene delivery

D Lin, X Feng, B Mai, X Li, F Wang, J Liu, X Liu… - Biomaterials, 2021 - Elsevier
Precise targeting and high therapeutic efficiency are the major requisites of personalized
cancer treatment. However, some unique features of the tumor microenvironment (TME) …

Bacteria-inspired nanomedicine

M Holay, Z Guo, J Pihl, J Heo, JH Park… - ACS applied bio …, 2020 - ACS Publications
The natural world has provided a host of materials and inspiration for the field of
nanomedicine. By taking design cues from naturally occurring systems, the …

[HTML][HTML] Bacteria and bacterial derivatives as delivery carriers for immunotherapy

SR Kang, DH Nguyen, SW Yoo, JJ Min - Advanced Drug Delivery Reviews, 2022 - Elsevier
There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …

[HTML][HTML] Engineered bacteria-based living materials for biotherapeutic applications

R Omer, MZ Mohsin, A Mohsin, BS Mushtaq… - … in Bioengineering and …, 2022 - frontiersin.org
Future advances in therapeutics demand the development of dynamic and intelligent living
materials. The past static monofunctional materials shall be unable to meet the requirements …

Decorated bacteria and the application in drug delivery

F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …

Bacterially mediated drug delivery and therapeutics: Strategies and advancements

L Wu, F Bao, L Li, X Yin, Z Hua - Advanced drug delivery reviews, 2022 - Elsevier
It was already clinically apparent 150 years ago that bacterial therapy could alleviate
diseases. Recently, a burgeoning number of researchers have been using bacterial …