Abstract Type 2 Diabetes (T2D) is an emerging public health problem in Asia. Although
ethnic specific mtDNA polymorphisms have been shown to contribute to T2D risk, the …

Aims/hypothesis This multinational study was conducted to investigate the association
between a mitochondrial DNA (mtDNA) T16189C polymorphism and type 2 diabetes in …

Mitochondrial dysfunction involves defective insulin secretion by pancreatic beta-cells, and
insulin resistance in insulin-sensitive tissues such as muscle and adipose tissue …

Mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) is a mitochondrial-derived
peptide that attenuates weight gain and hyperinsulinemia when administered to high fat-fed …

Mitochondrial DNA (mtDNA) variants have been implicated in many diseases including
diabetes mellitus. To explore whether these genetic variants contribute to the susceptibility …

Objective: The suggested correlation between a T-to-C transition at the nucleotide 16189 in
mitochondrial DNA (mtDNA) with increasing insulin resistance and adult-onset diabetes …

MOTS‐c is an exercise mimetic and improves insulin sensitivity in aged and diet‐induced
obese mice. Although plasma markers are good markers for the metabolic condition …

A hospital-based case-control study was conducted to investigate potential association
between mitochondrial DNA and Type 2 diabetes mellitus (T2DM) in Chinese Uyghur …

Background Recent genome-wide association studies searching for candidate susceptibility
loci for common complex diseases such as type 2 diabetes mellitus (T2DM) and its common …

Mitochondria play an important role in many processes, like glucose metabolism, fatty acid
oxidation and ATP synthesis. In this study, we aimed to identify association of common …