Background Chronic obstructive pulmonary disease (COPD) is a major health problem
associated with high mortality worldwide. Cigarette smoke (CS) exposure is the main cause …

Background Receptor-interacting protein kinase 1 (RIPK1) is a key mediator of regulated
cell death (including apoptosis and necroptosis) and inflammation, both drivers of COPD …

Introduction Bronchial epithelial cell death and airway inflammation induced by cigarette
smoke (CS) have been involved in the pathogenesis of COPD. GRP78, belonging to heat …

Background GLI pathogenesis-related 1 (GLIPR1) was originally identified in glioblastomas
and its expression was also found to be down-regulated in prostate cancer. Functional …

Background and purpose: Chronic obstructive pulmonary disease (COPD) is characterized
by progressive alveolar damage and generally irreversible airflow limitation. Nuclear factor …

Background Chronic obstructive pulmonary disease (COPD) is a significant public health
problem characterized by persistent airflow limitation. Despite previous research into the …

Smoke inhalation injury is an acute pathological change caused by thermal stimulation or
toxic substance absorption through respiratory epithelial cells. This study aims to probe the …

Chronic obstructive pulmonary disease (COPD) is a severe public health threat world-wide.
Cigarette smoke (CS)-induced airway epithelial cell death is a major pathway of …

Aims Pyroptosis and inflammation are involved in the development of chronic obstructive
pulmonary disease (COPD). However, the cigarette smoke-mediated mechanism of COPD …

Cigarette smoke is a major cause of chronic obstructive pulmonary disease (COPD). Airway
epithelial cells and macrophages are the first defense cells against cigarette smoke and …