Recent progress of exosomes in multiple myeloma: pathogenesis, diagnosis, prognosis and therapeutic strategies

X Wang, L He, X Huang, S Zhang, W Cao, F Che… - Cancers, 2021 - mdpi.com
Simple Summary In the pathogenesis of multiple myeloma (MM), some exosomes act on
different cells in the bone marrow microenvironment, which can create an environment …

[HTML][HTML] Potential therapeutic roles of exosomes in multiple myeloma: a systematic review

M Li, B Xia, Y Wang, MJ You, Y Zhang - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Multiple myeloma (MM) is the second most prevalent hematological malignancy. In spite of
the remarkable progress in understanding the biology and therapy of MM, curing this …

The emerging role of exosomes in multiple myeloma

M Moloudizargari, M Abdollahi, MH Asghari, AA Zimta… - Blood Reviews, 2019 - Elsevier
Multiple myeloma (MM), one of the most prevalent hematological malignancies, accounts for
approximately 10% of all blood cancers. In spite of the recent advancements in MM therapy …

[HTML][HTML] Exosomes in the pathogenesis and treatment of multiple myeloma in the context of the bone marrow microenvironment

T Chen, M Moscvin, G Bianchi - Frontiers in Oncology, 2020 - frontiersin.org
Multiple myeloma (MM), the second most common hematological malignancy, is an
incurable cancer of plasma cells. MM cells diffusely involves the bone marrow (BM) and …

Multiple myeloma cell-derived exosomes: Implications on tumorigenesis, diagnosis, prognosis and therapeutic strategies

A Allegra, M Di Gioacchino, A Tonacci, C Petrarca… - Cells, 2021 - mdpi.com
Multiple myeloma (MM) is a hematological disease that is still not curable. The bone marrow
milieu, with cellular and non-cellular elements, participate in the creation of a pro-tumoral …

Exosomes in multiple myeloma: from bench to bedside

E Menu, K Vanderkerken - Blood, The Journal of the American …, 2022 - ashpublications.org
Multiple myeloma (MM) remains an incurable plasma cell malignancy that develops in the
bone marrow (BM). This BM is partially responsible for protecting the MM cells against …

Inhibition of multiple myeloma‑derived exosomes uptake suppresses the functional response in bone marrow stromal cell

Y Zheng, C Tu, J Zhang, J Wang - … Journal of Oncology, 2019 - spandidos-publications.com
The communication between multiple myeloma (MM) cells and bone marrow stromal cells
(BMSCs) serves a pivotal role in MM progression by supporting MM cell growth, proliferation …

Involvement of MM cell‑derived exosomes in T lymphocytes immune responses

Q Shao, L Deng, H Liu, Z Liu, J Chen… - Oncology …, 2020 - spandidos-publications.com
Exosomes were reported to mediate cell communication in the tumor microenvironment;
however, the effects of multiple myeloma (MM)‑derived exosomes on the quantity and …

Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts

S Faict, J Muller, K De Veirman, E De Bruyne… - Blood cancer …, 2018 - nature.com
Progression of multiple myeloma (MM) is largely dependent on the bone marrow (BM)
microenvironment wherein communication through different factors including extracellular …

[HTML][HTML] The role of exosomes in the progression and therapeutic resistance of hematological malignancies

H Wang, Y You, X Zhu - Frontiers in Oncology, 2022 - frontiersin.org
Exosomes are membrane limited structures which derive from cell membranes and
cytoplasm. When released into extracellular space, they circulate through the extracellular …