Background: Although it is known that the brain communicates with the gastrointestinal (GI)
tract via the well-established gut-brain axis, the influence exerted by chronic intestinal …

Systemic inflammation and neuroinflammation affect the natural course of the sporadic form
of Alzheimer's disease (AD), as supported by epidemiological and preclinical data, and …

Background Alzheimer's disease (AD) is one of the neurodegenerative diseases and
characterized by the appearance and accumulation of amyloid-β (Aβ) aggregates and …

Amyloid plaques in Alzheimer's disease (AD) are associated with inflammation. Recent
studies demonstrated the involvement of the gut in cerebral amyloid-beta (Aβ) pathogenesis; …

Alzheimer's disease (AD) is characterized by progressive cognitive decline and is a leading
cause of death in the United States. Neuroinflammation has been implicated in the …

Systemic inflammation has been implicated in the progression of Alzheimer's disease (AD);
however, less is understood about how existing AD pathology contributes to adverse …

Alzheimer's disease (AD) is a neurodegenerative disorder histologically characterized by
amyloid-ß (Aß) protein accumulation and activation of associated microglia. Although these …

Chronic inflammatory bowel disorders (IBD) are idiopathic diseases associated with altered
intestinal permeability, which in turn causes an exaggerated immune response to enteric …

Inflammation plays an important role in the pathogenesis of Alzheimer's disease (AD). Some
evidence suggests that misfolded protein aggregates found in AD brains may have …

Abstract Background Beyond cognitive decline, Alzheimer's disease (AD) is characterized
by numerous neuropathological changes in the brain. Although animal models generally do …