Autophagy‐dependent ferroptosis as a therapeutic target in cancer
L Liu, L Li, M Li, Z Luo - ChemMedChem, 2021 - Wiley Online Library
Ferroptosis is an iron‐dependent form of cell death associated with the accumulation of
labile iron and cytotoxic lipid peroxides. Increasing evidence reveals that ferroptosis is not a …
labile iron and cytotoxic lipid peroxides. Increasing evidence reveals that ferroptosis is not a …
[HTML][HTML] Recent advances of ferroptosis in tumor: From biological function to clinical application
S Hu, Y Chu, X Zhou, X Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ferroptosis is a recently recognized form of cell death with distinct features in terms of
morphology, biochemistry, and molecular mechanisms. Unlike other types of cell death …
morphology, biochemistry, and molecular mechanisms. Unlike other types of cell death …
[HTML][HTML] The crosstalk between autophagy and ferroptosis: what can we learn to target drug resistance in cancer?
Y Zhou, Y Shen, C Chen, X Sui, J Yang… - Cancer biology & …, 2019 - ncbi.nlm.nih.gov
Autophagy is a conserved intracellular degradation system that plays a dual role in cell
death; thus, therapies targeting autophagy in cancer are somewhat controversial …
death; thus, therapies targeting autophagy in cancer are somewhat controversial …
Autophagy-dependent ferroptosis in cancer
Significance: Autophagy is a self-degrading process that determines cell fate in response to
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …
Ferroptosis is a type of autophagy-dependent cell death
Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …
and recycling system that, in a context-dependent manner, can either promote cell survival …
Recent progress on targeting ferroptosis for cancer therapy
G Xu, H Wang, X Li, R Huang, L Luo - Biochemical Pharmacology, 2021 - Elsevier
Ferroptosis is a new mode of cell death different from cell necrosis, autophagy, apoptosis,
and pyroptosis, which depends on the accumulation of reactive oxygen species (ROS) …
and pyroptosis, which depends on the accumulation of reactive oxygen species (ROS) …
Autophagy mediates an amplification loop during ferroptosis
S Lee, N Hwang, BG Seok, S Lee, SJ Lee… - Cell Death & …, 2023 - nature.com
Ferroptosis, a programmed cell death, has been identified and associated with cancer and
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …
Emerging mechanisms and targeted therapy of ferroptosis in cancer
H Wang, Y Cheng, C Mao, S Liu, D Xiao, J Huang… - Molecular Therapy, 2021 - cell.com
Ferroptosis is an iron-and lipid reactive oxygen species (ROS)-dependent form of
programmed cell death that is distinct from other forms of regulatory cell death at the …
programmed cell death that is distinct from other forms of regulatory cell death at the …
Ferroptosis nanomedicine: clinical challenges and opportunities for modulating tumor metabolic and immunological landscape
H Yang, X Yao, Y Liu, X Shen, M Li, Z Luo - Acs Nano, 2023 - ACS Publications
Ferroptosis, a type of regulated cell death driven by iron-dependent phospholipid
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …
Pharmacological targeting of ferroptosis in cancer treatment
MR Valashedi, A Nikoo… - Current Cancer Drug …, 2022 - ingentaconnect.com
Ferroptosis is a non-apoptotic mode of Regulated Cell Death (RCD) driven by excessive
accumulation of toxic lipid peroxides and iron overload. Ferroptosis could be triggered by …
accumulation of toxic lipid peroxides and iron overload. Ferroptosis could be triggered by …