[HTML][HTML] Immune cells in the BBB disruption after acute ischemic stroke: targets for immune therapy?

Y Qiu, C Zhang, A Chen, H Wang, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

The peripheral immune response after stroke—A double edge sword for blood‐brain barrier integrity

Y Li, ZY Zhu, TT Huang, YX Zhou… - CNS neuroscience & …, 2018 - Wiley Online Library
The blood‐brain barrier (BBB) is a highly regulated interface that separates the peripheral
circulation and the brain. It plays a vital role in regulating the trafficking of solutes, fluid, and …

Immune cells after ischemic stroke onset: roles, migration, and target intervention

L Ao, YY Yan, L Zhou, C Li, WT Li, W Fang… - Journal of Molecular …, 2018 - Springer
Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …

[HTML][HTML] The involvement and therapy target of immune cells after ischemic stroke

Z Jian, R Liu, X Zhu, D Smerin, Y Zhong, L Gu… - Frontiers in …, 2019 - frontiersin.org
After ischemic stroke, the integrity of the blood-brain barrier is compromised. Peripheral
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …

Neuroinflammation, stroke, blood-brain barrier dysfunction, and imaging modalities

E Candelario-Jalil, RM Dijkhuizen, T Magnus - Stroke, 2022 - Am Heart Assoc
Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …

The dual role of microglia in blood-brain barrier dysfunction after stroke

R Kang, M Gamdzyk, C Lenahan, J Tang… - Current …, 2020 - ingentaconnect.com
It is well-known that stroke is one of the leading causes of death and disability all over the
world. After a stroke, the blood-brain barrier subsequently breaks down. The BBB consists of …

Crosstalk between Inflammation and the BBB in Stroke

Y Huang, S Chen, Y Luo, Z Han - Current neuropharmacology, 2020 - ingentaconnect.com
The blood-brain barrier (BBB), which is located at the interface between the central nervous
system (CNS) and the circulatory system, is instrumental in establishing and maintaining the …

[HTML][HTML] Glial cells: role of the immune response in ischemic stroke

S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …

Macrophage and monocyte subsets in response to ischemic stroke

N Blank‐Stein, E Mass - European Journal of Immunology, 2023 - Wiley Online Library
Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …

[HTML][HTML] The translational potential of microglia and monocyte-derived macrophages in ischemic stroke

EE Wicks, KR Ran, JE Kim, R Xu, RP Lee… - Frontiers in …, 2022 - frontiersin.org
The immune response to ischemic stroke is an area of study that is at the forefront of stroke
research and presents promising new avenues for treatment development. Upon cerebral …