Congenital hypogonadotropic hypogonadism (CHH) is a clinically and genetically
heterogeneous congenital disease. Symptoms cover a wide spectrum from mild forms to …

Congenital hypogonadotropic hypogonadism (CHH) is a rare endocrine disorder that results
in reproductive hormone deficiency and reduced potential for fertility in adult life. Discoveries …

Hypogonadotropic hypogonadism (HH) often manifests as pubertal delay. A considerable
proportion of cases of HH is due to genetic mutations. Recognizing those mutated genes …

Hypogonadotropic hypogonadism, which may be normosmic (nHH) or anosmic/hyposmic,
known as Kallmann syndrome (KS), is due to gonadotropin-releasing hormone deficiency …

Male congenital hypogonadotropic hypogonadism (CHH) is a heterogenous group of
genetic disorders that cause impairment in the production or action of gonadotropin …

A genetic basis of congenital isolated hypogonadotropic hypogonadism (CHH) can be
defined in almost 50% of cases, albeit not necessarily the complete genetic basis. Next …

OBJECTIVE: To characterize the phenotype, modes of inheritance, karyotype, and molecular
basis of patients with idiopathic hypogonadotropic hypogonadism (IHH). DESIGN: Review of …

Objective To clarify the molecular basis of hypogonadotropic hypogonadism (HH). Design
Genome-wide copy number analysis by array-based comparative genomic hybridization …

Mutations in several genes have been shown to cause hypogonadotropic hypogonadism
(HHG) in humans. This condition may result from abnormalities in hypothalamic …

Congenital hypogonadotropic hypogonadism (CHH) and Kallmann syndrome (KS) are rare,
related diseases that prevent normal pubertal development and cause infertility in affected …