The galloyl moiety enhances the inhibitory activity of catechins and theaflavins against α-glucosidase by increasing the polyphenol–enzyme binding interactions
The inhibition properties of 10 tea polyphenols against α-glucosidase were studied through
inhibition assay, inhibition kinetics, fluorescence quenching and molecular docking. It was …
inhibition assay, inhibition kinetics, fluorescence quenching and molecular docking. It was …
Number of galloyl moiety and intramolecular bonds in galloyl-based polyphenols affect their interaction with alpha-glucosidase
The inhibition of α-glucosidase by nine galloyl-based polyphenols with free and unfree
galloyl moieties (GMs) was studied. The results show that the inhibitory activity increased …
galloyl moieties (GMs) was studied. The results show that the inhibitory activity increased …
Number of galloyl moieties and molecular flexibility are both important in alpha-amylase inhibition by galloyl-based polyphenols
The inhibition of porcine pancreatic α-amylase (PPA) by 9 galloyl-based polyphenols was
evaluated via initial digestion velocity, IC50, inhibition kinetics, fluorescence quenching and …
evaluated via initial digestion velocity, IC50, inhibition kinetics, fluorescence quenching and …
Young apple polyphenols as natural α-glucosidase inhibitors: In vitro and in silico studies
In this study, the inhibitory activity of young apple polyphenols (YAP) on α-glucosidase was
investigated. Composition and inhibition analyses suggested that tannic acid (TA),(-) …
investigated. Composition and inhibition analyses suggested that tannic acid (TA),(-) …
Molecular insights into α‐glucosidase inhibition and antiglycation properties affected by the galloyl moiety in (−)‐epigallocatechin‐3‐gallate
Q Guan, L Tang, L Zhang, L Huang… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND Diabetes mellitus poses a substantial threat to public health due to rising
morbidity and mortality. α‐Glucosidase is one of the key enzymes affecting diabetes …
morbidity and mortality. α‐Glucosidase is one of the key enzymes affecting diabetes …
Inhibitory mechanism of novel allosteric inhibitor, Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves proanthocyanidins against α-glucosidase
Abstract α-Glucosidase is a key enzyme related to starch digestion and type-2 diabetes. In
the present study, the inhibition effect and the underlying mechanism of Chinese bayberry …
the present study, the inhibition effect and the underlying mechanism of Chinese bayberry …
Studies on the inhibition of α-glucosidase by biflavonoids and their interaction mechanisms
H Li, J Yang, M Wang, X Ma, X Peng - Food Chemistry, 2023 - Elsevier
Biflavonoids are a kind of polyphenol compounds with numerous biological functions.
However, the potential inhibitory activities of biflavonoids on α-glucosidase are yet unknown …
However, the potential inhibitory activities of biflavonoids on α-glucosidase are yet unknown …
α-Glucosidase inhibitory profile of catechins and theaflavins
T Matsui, T Tanaka, S Tamura, A Toshima… - Journal of agricultural …, 2007 - ACS Publications
To clarify the postprandial glucose suppression effect of flavonoids, the inhibitory effects of
catechins and theaflavins against α-glucosidase (AGH) were examined in this study. It was …
catechins and theaflavins against α-glucosidase (AGH) were examined in this study. It was …
Inhibition of α-glucosidase and α-amylase by flavonoid glycosides from Lu'an GuaPian tea: molecular docking and interaction mechanism
Green tea may favorably modulate blood glucose homeostasis, and regular consumption of
green tea can prevent the development of type 2 diabetes mellitus. In this study, α …
green tea can prevent the development of type 2 diabetes mellitus. In this study, α …
Advance in dietary polyphenols as α-glucosidases inhibitors: a review on structure-activity relationship aspect
The dietary polyphenols as α-glucosidases inhibitors have attracted great interest among
researchers. The aim of this review is to give an overview of the research reports on the …
researchers. The aim of this review is to give an overview of the research reports on the …
相关搜索
- catechins and theaflavins α glucosidase
- galloyl moiety α glucosidase
- galloyl moiety catechins and theaflavins
- galloyl moiety binding interactions
- catechins and theaflavins inhibitory activity
- galloyl moiety inhibitory activity
- binding interactions enzyme inhibition
- α glucosidases dietary polyphenols
- α glucosidase inhibitory activity
- α glucosidase interaction mechanism
- α glucosidase molecular docking
- galloyl moiety antiglycation properties
- galloyl moiety intramolecular bonds
- galloyl moiety molecular insights
- α glucosidase antiglycation properties
- α glucosidases relationship aspect