Cerebral blood flow predicts conversion of mild cognitive impairment into Alzheimer's disease and cognitive decline: an arterial spin labeling follow-up study

W Duan, GD Zhou… - Journal of …, 2021 - content.iospress.com
Background: This is the first longitudinal study to assess regional cerebral blood flow (rCBF)
changes during the progression from normal control (NC) through mild cognitive impairment …

Longitudinal cerebral blood flow changes in normal aging and the Alzheimer's disease continuum identified by arterial spin labeling MRI

A Camargo, Z Wang… - Journal of …, 2021 - content.iospress.com
Background: Cross-sectional studies have shown lower cerebral blood flow (CBF) in
Alzheimer's disease (AD), but longitudinal CBF changes in AD are still unknown. Objective …

Cerebral blood flow is associated with diagnostic class and cognitive decline in Alzheimer's disease

W Duan, P Sehrawat… - Journal of …, 2020 - content.iospress.com
Background: Reliable cerebral blood flow (CBF) biomarkers using a noninvasive imaging
technique are sought to facilitate early diagnosis and intervention in early Alzheimer's …

Arterial‐spin‐labeling (ASL) perfusion MRI predicts cognitive function in elderly individuals: a 4‐year longitudinal study

JB De Vis, SL Peng, X Chen, Y Li, P Liu… - Journal of Magnetic …, 2018 - Wiley Online Library
Background With the disappointing outcomes of clinical trials on patients with Alzheimer's
disease or mild cognitive impairment (MCI), there is increasing attention to understanding …

Regional cerebral blood flow in mild cognitive impairment and Alzheimer's disease measured with arterial spin labeling magnetic resonance imaging

A Sierra-Marcos - International journal of Alzheimer's disease, 2017 - Wiley Online Library
Alzheimer's disease (AD) depicts dynamic changes in regional brain function from early
stages of the disease. Arterial spin labeling‐(ASL‐) based MRI methods have been applied …

[HTML][HTML] Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia

CA Morgan, TR Melzer, RP Roberts, K Wiebels… - Scientific reports, 2021 - nature.com
Cerebral blood flow (CBF) measured with arterial spin labelling (ASL) magnetic resonance
imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time …

Cerebral blood flow measured with 3D pseudocontinuous arterial spin-labeling MR imaging in Alzheimer disease and mild cognitive impairment: a marker for disease …

MAA Binnewijzend, JPA Kuijer, MR Benedictus… - Radiology, 2013 - pubs.rsna.org
Purpose To compare quantitative cerebral blood flow (CBF) values in patients with
Alzheimer disease (AD), patients with mild cognitive impairment (MCI), and subjects with …

[HTML][HTML] Arterial spin labeled MRI in prodromal Alzheimer's disease: a multi-site study

Z Wang, SR Das, SX Xie, SE Arnold, JA Detre… - Neuroimage …, 2013 - Elsevier
We examined differences in cerebral blood flow (CBF) measured by Arterial Spin Labeled
perfusion MRI (ASL MRI) across the continuum from cognitively normal (CN) older adults to …

[HTML][HTML] Cerebral perfusion in the predementia stages of Alzheimer's disease

MAA Binnewijzend, MR Benedictus, JPA Kuijer… - European …, 2016 - Springer
Objectives To investigate arterial spin-labelling (ASL) cerebral blood flow (CBF) changes in
predementia stages of Alzheimer's disease (AD). Methods Data were obtained from 177 …

Subjective cognitive decline modifies the relationship between cerebral blood flow and memory function in cognitively normal older adults

CC Hays, ZZ Zlatar, L Campbell, MJ Meloy… - Journal of the …, 2018 - cambridge.org
Objectives: Subjective cognitive decline (SCD), or self-reported cognitive decline despite
normal neuropsychological test performance, is a risk factor for objective cognitive decline …