Reducing the cognitive footprint of brain tumor surgery

NB Dadario, B Brahimaj, J Yeung… - Frontiers in neurology, 2021 - frontiersin.org
The surgical management of brain tumors is based on the principle that the extent of
resection improves patient outcomes. Traditionally, neurosurgeons have considered that …

Brain connectomics applied to oncological neuroscience: from a traditional surgical strategy focusing on glioma topography to a meta-network approach

H Duffau - Acta Neurochirurgica, 2021 - Springer
The classical way for surgical selection and planning in cerebral glioma mainly focused on
tumor topography. The emerging science of connectomics, which aims of mapping brain …

New philosophy, clinical pearls, and methods for intraoperative cognition mapping and monitoring “à la carte” in brain tumor patients

H Duffau - Neurosurgery, 2021 - journals.lww.com
The purpose of surgery for brain tumors involving eloquent neural circuits is to maximize the
extent of resection while preserving an optimal quality of life. To this end, especially in …

Technical principles in glioma surgery and preoperative considerations

D Krivosheya, SS Prabhu, JS Weinberg… - Journal of Neuro …, 2016 - Springer
The goal of glioma surgery is maximal safe resection. These intrinsic brain neoplasms,
however, lack a clear margin and frequently infiltrate eloquent areas of the brain thus …

A connectomic atlas of the human cerebrum—Chapter 1: Introduction, methods, and significance

CM Baker, JD Burks, RG Briggs, AK Conner… - Operative …, 2018 - journals.lww.com
BACKGROUND As knowledge of the brain has increased, clinicians have learned that the
cerebrum is composed of complex networks that interact to execute key functions. While …

Mapping the horizon: techniques to optimize tumor resection before and during surgery

N Sanai, MS Berger - Neurosurgery, 2008 - journals.lww.com
Nader Sanai, MD, and Mitchel S. Berger, MD lthough a primary tenet of neurosurgical
oncology is that survival can improve with greater tumor resection, this principle must be …

The challenge to remove diffuse low-grade gliomas while preserving brain functions

H Duffau - Acta neurochirurgica, 2012 - Springer
WHO grade II glioma, ie diffuse low-grade glioma, is a pre-malignant tumour, usually
revealed by seizures in young patients with a normal life. This tumour has a constant growth …

Neurocognitive changes associated with surgical resection of left and right temporal lobe glioma

KR Noll, JS Weinberg, M Ziu, RJ Benveniste… - …, 2015 - journals.lww.com
BACKGROUND: Little is known regarding the neurocognitive impact of temporal lobe tumor
resection. OBJECTIVE: To clarify subacute surgery-related changes in neurocognitive …

Mapping the connectome in awake surgery for gliomas: an update.

H Duffau - Journal of neurosurgical sciences, 2017 - europepmc.org
The traditional principle underlying oncological neurosurgery is to remove a tumor mass
displacing the brain in order to increase survival. Recently, advances in connectomics …

Functional preoperative and intraoperative mapping and monitoring: increasing safety and efficacy in glioma surgery

M Ottenhausen, SM Krieg, B Meyer, F Ringel - Neurosurgical focus, 2015 - thejns.org
Greater extent of resection (EOR) of low-grade gliomas is associated with improved survival.
Proximity to eloquent cortical regions often limits resectability and elevates the risk of …