Simple Summary Glioblastomas (GBMs) are the most frequent and aggressive malignant
tumors arising in the human brain. One of the main reasons for GBM aggressiveness is its …

Glioblastoma (GBM) is the most common and malignant type of primary brain tumor. It
represents one of the deadliest human cancers, with an average survival at diagnosis of …

Heterogeneity is a hallmark of tumors and has a crucial role in the outcome of the
malignancy, because it not only confounds diagnosis, but also challenges the design of …

Glioblastomas,(grade 4 astrocytomas), are aggressive primary brain tumors characterized
by histopathological heterogeneity. High-resolution sequencing technologies have shown …

Glioblastoma (GBM) is one of the deadliest types of cancer and highly refractory to
chemoradiation and immunotherapy. One of the main reasons for this resistance to therapy …

Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumor in
adults. Despite extensive therapy the prognosis for GBM patients remains poor and the …

Glioblastoma is the most common intracranial malignancy and constitutes about 50% of all
gliomas. Both inter-tumor and intra-tumor histological heterogeneity had been recognized by …

Brain tumors remain one of the most difficult tumors to treat and, depending on the
diagnosis, have a poor prognosis. Of brain tumors, glioblastoma (GBM) is the most common …

Glioblastoma (GB) is the most common and aggressive primary brain malignancy, with poor
prognosis and a lack of effective therapeutic options. Accumulating evidence suggests that …

Glioblastoma (GBM), the most common primary malignant brain tumor in adults, is
associated with significant morbidity and mortality despite maximal safe resection followed …