[HTML][HTML] Maternal obesity and metabolic disorders associate with congenital heart defects in the offspring: A systematic review

G Hedermann, PL Hedley, IN Thagaard, L Krebs… - PLoS …, 2021 - journals.plos.org
Background Congenital heart defects (CHDs) are the most common congenital
malformations. The aetiology of CHDs is complex. Large cohort studies and systematic …

Maternal overweight and obesity and risk of congenital heart defects in offspring

J Brite, SK Laughon, J Troendle, J Mills - International journal of obesity, 2014 - nature.com
Objective: Obesity is a risk factor for congenital heart defects (CHDs), but whether risk is
independent of abnormal glucose metabolism remains unknown. Data on whether …

Maternal Diabetes and Overweight and Congenital Heart Defects in Offspring

R Turunen, A Pulakka, J Metsälä, T Vahlberg… - JAMA Network …, 2024 - jamanetwork.com
Importance Maternal diabetes and overweight or obesity are known to be associated with
increased risk of congenital heart defects (CHDs) in offspring, but there are no large studies …

Increased maternal Body Mass Index is associated with congenital heart defects: An updated meta-analysis of observational studies

Z Zheng, T Yang, L Chen, L Wang, S Zhang… - International journal of …, 2018 - Elsevier
Purpose To review and summarize the epidemiologic evidence on the association of
maternal Body Mass Index (BMI) with risk of congenital heart defects (CHDs) and to assess …

Pre-pregnancy obesity as a modifier of gestational diabetes and birth defects associations: a systematic review

AS Parnell, A Correa, EA Reece - Maternal and Child Health Journal, 2017 - Springer
Objective Inconsistent findings of associations between gestational diabetes mellitus (GDM)
and birth defects suggest unaccounted confounders may underlie the actual basis for such …

Maternal obesity and diabetes mellitus as risk factors for congenital heart disease in the offspring

E Helle, JR Priest - Journal of the American Heart Association, 2020 - Am Heart Assoc
Congenital heart disease (CHD) is the most common anatomical malformation occurring live‐
born infants and an increasing cause of morbidity and mortality across the lifespan and …

Maternal overweight and obesity and risk of congenital heart defects

M Persson, N Razaz, AK Edstedt Bonamy… - Journal of the American …, 2019 - jacc.org
Background: Congenital heart defects are more frequent in offspring of mothers with
overweight or obesity. However, associations between maternal overweight and obesity …

Pregestational diabetes mediates the association between maternal obesity and the risk of congenital heart defects

XX Wu, RX Ge, L Huang, FY Tian… - Journal of Diabetes …, 2022 - Wiley Online Library
Abstract Aims/Introduction We aimed to explore whether the association between obesity
and congenital heart defects (CHDs) can be mediated by maternal pregestational diabetes …

Association between maternal body mass index and congenital heart defects in offspring: a systematic review

G Cai, X Sun, L Zhang, Q Hong - American journal of obstetrics and …, 2014 - Elsevier
The aim of this study was to investigate the relationship between maternal body mass index
and all congenital heart defects (CHDs) combined and 11 individual defects. PubMed …

Prepregnancy body mass index and congenital heart defects among offspring: a population‐based study

NL Madsen, SM Schwartz, MB Lewin… - Congenital heart …, 2013 - Wiley Online Library
Objective The purpose of this study was to evaluate the association between fetal
development of congenital heart defects (CHD) and maternal prepregnancy body mass …