The impact of fatigue on corticospinal excitability and GABAergic inhibitory activity has been
relatively well studied in young adults. However, this is yet to be established in older adults …

Ageing is accompanied by neuromuscular changes which may alter fatigue in older adults.
These changes may include changes in corticospinal excitatory and inhibitory processes …

This review aims to characterize fatigue-related changes in corticospinal excitability and
inhibition in healthy subjects. Transcranial magnetic stimulation (TMS) has been extensively …

Neural drive originating in higher brain areas reaches exercising limb muscles through the
corticospinal‐motoneuronal pathway, which links the motor cortex and spinal …

BACKGROUND The impact of aging on exercise induced fatigue is inconclusive with many
studies ascribing a greater fatigue resistance to older individuals. PURPOSE To examine …

The effects of muscle fatigue are known to be altered in older adults, and age-related
changes in the brain are likely to be a contributing factor. However, the neural mechanisms …

It is unclear how old age affects the neuronal mechanisms of motor learning. We reviewed
the neuronal mechanisms of how healthy old and young adults acquire motor skills as …

This study compared the contribution of supraspinal fatigue to muscle fatigue in old and
young adults. Transcranial magnetic stimulation (TMS) of motor cortex was used to assess …

Introduction: Central fatigue refers to a reduced drive of motor cortical output during
exercise, and performance can be enhanced after training. However, the effects of training …

This study determined the contribution of supraspinal fatigue and contractile properties to
the age difference in neuromuscular fatigue during and recovery from a low-intensity …