[HTML][HTML] CRISPR-based strategies in infectious disease diagnosis and therapy
A Binnie, E Fernandes, H Almeida-Lousada… - Infection, 2021 - Springer
Purpose CRISPR gene-editing technology has the potential to transform the diagnosis and
treatment of infectious diseases, but most clinicians are unaware of its broad applicability …
treatment of infectious diseases, but most clinicians are unaware of its broad applicability …
[HTML][HTML] Blossom of CRISPR technologies and applications in disease treatment
Since 2013, the CRISPR-based bacterial antiviral defense systems have revolutionized the
genome editing field. In addition to genome editing, CRISPR has been developed as a …
genome editing field. In addition to genome editing, CRISPR has been developed as a …
[HTML][HTML] CRISPR-Cas technology: emerging applications in clinical microbiology and infectious diseases
S Serajian, E Ahmadpour, SMR Oliveira, ML Pereira… - Pharmaceuticals, 2021 - mdpi.com
Through the years, many promising tools for gene editing have been developed including
zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) …
zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) …
[HTML][HTML] A landscape of CRISPR/Cas technique for emerging viral disease diagnostics and therapeutics: progress and prospects
S Tripathi, P Khatri, Z Fatima, RP Pandey, S Hameed - Pathogens, 2022 - mdpi.com
Viral diseases have emerged as a serious threat to humanity and as a leading cause of
morbidity worldwide. Many viral diagnostic methods and antiviral therapies have been …
morbidity worldwide. Many viral diagnostic methods and antiviral therapies have been …
The CRISPR revolution and its potential impact on global health security
Global health security is constantly under threat from infectious diseases. Despite advances
in biotechnology that have improved diagnosis and treatment of such diseases, delays in …
in biotechnology that have improved diagnosis and treatment of such diseases, delays in …
CRISPR-Cas biology and its application to infectious diseases
JR Strich, DS Chertow - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Infectious diseases remain a global threat contributing to excess morbidity and death
annually, with the persistent potential for destabilizing pandemics. Improved understanding …
annually, with the persistent potential for destabilizing pandemics. Improved understanding …
[HTML][HTML] An update on the application of CRISPR technology in clinical practice
The CRISPR/Cas system, an innovative gene-editing tool, is emerging as a promising
technique for genome modifications. This straightforward technique was created based on …
technique for genome modifications. This straightforward technique was created based on …
[HTML][HTML] CRISPR-Cas system: from diagnostic tool to potential antiviral treatment
This mini review focuses on the diagnosis and treatment of virus diseases using Crisper-Cas
technology. The present paper describes various strategies involved in diagnosing diseases …
technology. The present paper describes various strategies involved in diagnosing diseases …
[HTML][HTML] Harnessing CRISPR technology for viral therapeutics and vaccines: from preclinical studies to clinical applications
F Zahedipour, F Zahedipour, P Zamani, MR Jaafari… - Virus Research, 2024 - Elsevier
The CRISPR/Cas system, identified as a type of bacterial adaptive immune system, have
attracted significant attention due to its remarkable ability to precisely detect and eliminate …
attracted significant attention due to its remarkable ability to precisely detect and eliminate …
[HTML][HTML] Harnessing CRISPR to combat human viral infections
H De Buhr, RJ Lebbink - Current Opinion in Immunology, 2018 - Elsevier
Highlights•CRISPR can combat pathogenic human viruses.•Targeting viral DNA directly
abrogates infection and replication.•CRISPR can excise and disrupt integrated viral DNA in …
abrogates infection and replication.•CRISPR can excise and disrupt integrated viral DNA in …