[HTML][HTML] CRISPR-based strategies in infectious disease diagnosis and therapy

A Binnie, E Fernandes, H Almeida-Lousada… - Infection, 2021 - Springer
Purpose CRISPR gene-editing technology has the potential to transform the diagnosis and
treatment of infectious diseases, but most clinicians are unaware of its broad applicability …

[HTML][HTML] Blossom of CRISPR technologies and applications in disease treatment

H Liu, L Wang, Y Luo - Synthetic and Systems Biotechnology, 2018 - Elsevier
Since 2013, the CRISPR-based bacterial antiviral defense systems have revolutionized the
genome editing field. In addition to genome editing, CRISPR has been developed as a …

[HTML][HTML] CRISPR-Cas technology: emerging applications in clinical microbiology and infectious diseases

S Serajian, E Ahmadpour, SMR Oliveira, ML Pereira… - Pharmaceuticals, 2021 - mdpi.com
Through the years, many promising tools for gene editing have been developed including
zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) …

[HTML][HTML] A landscape of CRISPR/Cas technique for emerging viral disease diagnostics and therapeutics: progress and prospects

S Tripathi, P Khatri, Z Fatima, RP Pandey, S Hameed - Pathogens, 2022 - mdpi.com
Viral diseases have emerged as a serious threat to humanity and as a leading cause of
morbidity worldwide. Many viral diagnostic methods and antiviral therapies have been …

The CRISPR revolution and its potential impact on global health security

KE Watters, J Kirkpatrick, MJ Palmer… - Pathogens and global …, 2021 - Taylor & Francis
Global health security is constantly under threat from infectious diseases. Despite advances
in biotechnology that have improved diagnosis and treatment of such diseases, delays in …

CRISPR-Cas biology and its application to infectious diseases

JR Strich, DS Chertow - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Infectious diseases remain a global threat contributing to excess morbidity and death
annually, with the persistent potential for destabilizing pandemics. Improved understanding …

[HTML][HTML] An update on the application of CRISPR technology in clinical practice

F Morshedzadeh, M Ghanei, M Lotfi, M Ghasemi… - Molecular …, 2024 - Springer
The CRISPR/Cas system, an innovative gene-editing tool, is emerging as a promising
technique for genome modifications. This straightforward technique was created based on …

[HTML][HTML] CRISPR-Cas system: from diagnostic tool to potential antiviral treatment

A Rajan, S Shrivastava, Janhawi, A Kumar… - Applied Microbiology …, 2022 - Springer
This mini review focuses on the diagnosis and treatment of virus diseases using Crisper-Cas
technology. The present paper describes various strategies involved in diagnosing diseases …

[HTML][HTML] Harnessing CRISPR technology for viral therapeutics and vaccines: from preclinical studies to clinical applications

F Zahedipour, F Zahedipour, P Zamani, MR Jaafari… - Virus Research, 2024 - Elsevier
The CRISPR/Cas system, identified as a type of bacterial adaptive immune system, have
attracted significant attention due to its remarkable ability to precisely detect and eliminate …

[HTML][HTML] Harnessing CRISPR to combat human viral infections

H De Buhr, RJ Lebbink - Current Opinion in Immunology, 2018 - Elsevier
Highlights•CRISPR can combat pathogenic human viruses.•Targeting viral DNA directly
abrogates infection and replication.•CRISPR can excise and disrupt integrated viral DNA in …