Chronic bronchitis (CB) is associated with more dyspnea, increased respiratory
exacerbations, reduced exercise capacity, and mortality [1]. The hallmark of CB is mucus …

Importance Airway mucus plugs are common in patients with chronic obstructive pulmonary
disease (COPD); however, the association of airway mucus plugging and mortality in …

Background Airway mucus plugs are frequently identified on CT scans of patients with
COPD with a smoking history without mucus-related symptoms (ie, cough, phlegm [silent …

Background Airway wall thickening and excess airway mucus occur in asthma and chronic
obstructive pulmonary disease (COPD), but few studies have investigated the relationship …

Background Mucous exudates occluding the lumen of small airways are associated with
reduced lung function and mortality in subjects with COPD; however, luminal plugs in large …

Rationale: The relative roles of mucus plugs and emphysema in mechanisms of airflow
limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) …

Abstract Background and Objective Mucus plugs and underlying airway tree structure can
affect airflow limitation and prognosis in patients with chronic obstructive pulmonary disease …

Much has been written about mucus accumulation and plugging of the airway lumen as
pathologic features of asthma. Sir William Osler (1849–1919) made early clinical …

Background Goblet cell hyperplasia is a classic but variable pathologic finding in COPD.
Current literature shows that smoking is a risk factor for chronic bronchitis but the …

Coughing up phlegm from the chest is one of the most common respiratory symptoms and
can be observed in most lung diseases. Yet, although highly prevalent among patients with …