Sendai virus-vectored vaccines that express envelope glycoproteins of respiratory viruses

CJ Russell, JL Hurwitz - Viruses, 2021 - mdpi.com
Human respiratory syncytial virus (HRSV), human metapneumovirus (HMPV), and human
parainfluenza viruses (HPIVs) are leading causes of respiratory disease in young children …

Sendai virus as a backbone for vaccines against RSV and other human paramyxoviruses

CJ Russell, JL Hurwitz - Expert review of vaccines, 2016 - Taylor & Francis
Human paramyxoviruses are the etiological agents for life-threatening respiratory virus
infections of infants and young children. These viruses, including respiratory syncytial virus …

Development of recombinant Sendai virus vaccines for prevention of human parainfluenza and respiratory syncytial virus infections

JL Hurwitz - The Pediatric infectious disease journal, 2008 - journals.lww.com
Respiratory syncytial virus (RSV) and human parainfluenza viruses (hPIVs) are the most
important causes of hospitalization for viral respiratory tract diseases in infants and young …

Human PIV-2 recombinant Sendai virus (rSeV) elicits durable immunity and combines with two additional rSeVs to protect against hPIV-1, hPIV-2, hPIV-3, and RSV

B Jones, X Zhan, V Mishin, KS Slobod, S Surman… - Vaccine, 2009 - Elsevier
The human parainfluenza viruses (hPIVs) and respiratory syncytial viruses (RSVs) are the
leading causes of hospitalizations due to respiratory viral disease in infants and young …

Sendai virus recombinant vaccine expressing hPIV-3 HN or F elicits protective immunity and combines with a second recombinant to prevent hPIV-1, hPIV-3 and RSV …

X Zhan, KS Slobod, S Krishnamurthy, LE Luque… - Vaccine, 2008 - Elsevier
The human parainfluenza viruses (hPIVs) and respiratory syncytial virus (RSV) are the
leading causes of serious respiratory illness in the human pediatric population. Despite …

Recombinant Sendai virus as a novel vaccine candidate for respiratory syncytial virus

T Takimoto, JL Hurwitz, X Zhan, S Krishnamurthy… - Viral …, 2005 - liebertpub.com
Respiratory syncytial virus (RSV) is among the most important and serious pediatric
respiratory diseases, and yet after more than four decades of research an effective vaccine …

Sendai virus recombinant vaccine expressing a secreted, unconstrained respiratory syncytial virus fusion protein protects against RSV in cotton rats

X Zhan, KS Slobod, BG Jones, RE Sealy… - International …, 2015 - academic.oup.com
The respiratory syncytial virus (RSV) is responsible for as many as 199000 annual deaths
worldwide. Currently, there is no standard treatment for RSV disease and no vaccine …

Safety and immunogenicity of an intranasal sendai virus-based vaccine for human parainfluenza virus type I and respiratory syncytial virus (SeVRSV) in adults

F Scaggs Huang, DI Bernstein, KS Slobod… - Human Vaccines & …, 2021 - Taylor & Francis
SeVRSV is a replication-competent Sendai virus (SeV)-based vaccine carrying the
respiratory syncytial virus (RSV) fusion protein (F) gene. Unmanipulated, non-recombinant …

Sendai virus-based RSV vaccine protects against RSV challenge in an in vivo maternal antibody model

BG Jones, RE Sealy, SL Surman, A Portner, CJ Russell… - Vaccine, 2014 - Elsevier
Respiratory syncytial virus (RSV) is the cause of significant morbidity and mortality among
infants, and despite decades of research there remains no licensed vaccine. SeVRSV is a …

Recombinant Sendai virus expressing the G glycoprotein of respiratory syncytial virus (RSV) elicits immune protection against RSV

T Takimoto, JL Hurwitz, C Coleclough… - Journal of …, 2004 - Am Soc Microbiol
Although RSV causes serious pediatric respiratory disease, an effective vaccine does not
exist. To capture the strengths of a live virus vaccine, we have used the murine …