A resource for improved predictions of Trypanosoma and Leishmania protein three-dimensional structure

RJ Wheeler - PLoS One, 2021 - journals.plos.org
AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

IntFOLD: an integrated web resource for high performance protein structure and function prediction

LJ McGuffin, R Adiyaman, AHA Maghrabi… - Nucleic acids …, 2019 - academic.oup.com
The IntFOLD server provides a unified resource for the automated prediction of: protein
tertiary structures with built-in estimates of model accuracy (EMA), protein structural domain …

Before and after AlphaFold2: An overview of protein structure prediction

LMF Bertoline, AN Lima, JE Krieger… - Frontiers in …, 2023 - frontiersin.org
Three-dimensional protein structure is directly correlated with its function and its
determination is critical to understanding biological processes and addressing human …

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

M Varadi, S Anyango, M Deshpande, S Nair… - Nucleic acids …, 2022 - academic.oup.com
Abstract The AlphaFold Protein Structure Database (AlphaFold DB, https://alphafold. ebi. ac.
uk) is an openly accessible, extensive database of high-accuracy protein-structure …

The trRosetta server for fast and accurate protein structure prediction

Z Du, H Su, W Wang, L Ye, H Wei, Z Peng… - Nature protocols, 2021 - nature.com
The trRosetta (transform-restrained Rosetta) server is a web-based platform for fast and
accurate protein structure prediction, powered by deep learning and Rosetta. With the input …

Critical assessment of methods of protein structure prediction: Progress and new directions in round XI

J Moult, K Fidelis, A Kryshtafovych… - Proteins: Structure …, 2016 - Wiley Online Library
Modeling of protein structure from amino acid sequence now plays a major role in structural
biology. Here we report new developments and progress from the CASP11 community …

Efficient and accurate prediction of protein structure using RoseTTAFold2

M Baek, I Anishchenko, IR Humphreys, Q Cong… - BioRxiv, 2023 - biorxiv.org
AlphaFold2 and RoseTTAFold predict protein structures with very high accuracy despite
substantial architecture differences. We sought to develop an improved method combining …

Protein structure prediction using Rosetta in CASP12

S Ovchinnikov, H Park, DE Kim… - Proteins: Structure …, 2018 - Wiley Online Library
We describe several notable aspects of our structure predictions using Rosetta in CASP12
in the free modeling (FM) and refinement (TR) categories. First, we had previously …

Protein structure prediction in the deep learning era

Z Peng, W Wang, R Han, F Zhang, J Yang - Current Opinion in Structural …, 2022 - Elsevier
Significant advances have been achieved in protein structure prediction, especially with the
recent development of the AlphaFold2 and the RoseTTAFold systems. This article reviews …

Recent progress of protein tertiary structure prediction

Q Wuyun, Y Chen, Y Shen, Y Cao, G Hu, W Cui, J Gao… - Molecules, 2024 - mdpi.com
The prediction of three-dimensional (3D) protein structure from amino acid sequences has
stood as a significant challenge in computational and structural bioinformatics for decades …