Introduction Aims of this study were (a) to assess the development ratio of hyponatremia
during treatment with linezolid and (b) to evaluate the relationship between the risk of …

Linezolid is an oxazolidinone antibiotic against Gram-positive bacteria. Although
thrombocytopenia is a major adverse effect of linezolid, hyponatremia also often develops …

Several cases of severe hyponatremia induced by linezolid (LZD) were reported. However,
severe infections could also cause hyponatremia by increasing vasopressin secretion. To …

Background The use of linezolid has increased with the emergence of multidrug-resistant
bacteria. Serum lactic acidosis has been reported as a serious side effect of linezolid use …

Purpose A probable case of syndrome of inappropriate antidiuretic hormone secretion
(SIADH) due to linezolid use is reported. Summary An 81-year-old Korean woman …

Retrospective studies have documented a significant association between linezolid (LNZ)
plasma concentrations and drug-related haematological toxicity. However, the safe upper …

Some studies have shown that adjustments to the linezolid dose guided by therapeutic drug
monitoring (TDM) can reduce interindividual variability in drug exposure and improve …

The major adverse event associated with linezolid treatment is reversible myelosuppression,
mostly thrombocytopenia. Recent studies have reported that the incidence of linezolid …

Objectives Thrombocytopenia is sometimes observed during linezolid therapy. Here, we
aimed to investigate the factors affecting linezolid-induced thrombocytopenia. Methods A …

Background Linezolid is administered as a fixed dose to all patients despite evidence of
overexposure and thrombocytopenia in renal impairment. The aims of this study were to …