Laser Doppler Flowmetry Recording for Rodent Stroke Model Confirmation

S Singh, G Garg, AK Verma, AK Singh - Models and Techniques in Stroke …, 2021 - Springer
The assessment of cerebral blood flow (CBF) during cerebral and spinal ischemia and
reperfusion with conventional methods such as hydrogen removal and autoradiography of …

Blood Flow Reduction: Laser Doppler, 14C-IAP

F Zhang, SH Graham, J Chen - … Models of Acute Neurological Injuries II …, 2012 - Springer
Ischemic strokes are caused by a sharp fall of the cerebral blood flow (CBF) to certain
regions of brain tissues. In experimental research of cerebral ischemia, the animal models …

Laser Doppler flowmetry of focal ischaemia and reperfusion in deep brain structures in rats

W Reith, M Forsting, J Weber, R Stingele, W Hacke… - Acta …, 1994 - Springer
Monitoring cerebral blood flow during focal ischaemia and reperfusion with established
techniques such as hydrogen clearance and autoradiography is difficult. Laser Doppler …

Laser Doppler flowmetry in non-human primate stroke studies: model refinement for pre-clinical development of cerebroprotective strategies

CJ Winfree, WJ Mack, D Hoh, R King, AF Ducruet… - Acta …, 2003 - Springer
Summary¶ Background. Safety, feasibility, and efficacy trials in non-human primate stroke
models are essential to the evaluation of experimental therapies and their translation to …

Laser Doppler flowmetry to measure changes in cerebral blood flow

BA Sutherland, T Rabie, AM Buchan - Cerebral Angiogenesis: Methods …, 2014 - Springer
Laser Doppler flowmetry (LDF) is a method by which relative cerebral blood flow (CBF) of
the cortex can be measured. Although the method is easy to employ, LDF only measures …

Continuous measurement of cerebral cortical blood flow by laser—Doppler flowmetry in a rat stroke model

U Dirnagl, B Kaplan, M Jacewicz… - Journal of Cerebral …, 1989 - journals.sagepub.com
Laser-Doppler flowmetry (LDF), a new method allowing instantaneous, continuous, and
noninvasive measurements of microcirculatory blood flow in a small tissue sample, was …

Optimized system for cerebral perfusion monitoring in the rat stroke model of intraluminal middle cerebral artery occlusion

S Beretta, M Riva, D Carone, E Cuccione… - JoVE (Journal of …, 2013 - jove.com
The translational potential of pre-clinical stroke research depends on the accuracy of
experimental modeling. Cerebral perfusion monitoring in animal models of acute ischemic …

On the number of measurement sites required to assess regional cerebral blood flow by laser-Doppler scanning during cerebral ischemia and reperfusion

M Soehle, A Heimann, O Kempski - Journal of neuroscience methods, 2001 - Elsevier
The aim of this study was to determine whether the number of measurement sites affected
the precision of regional cerebral blood flow (CBF) assessment by Laser-Doppler (LD). A …

Laser Doppler flowmetry predicts occlusion but not tPA-mediated reperfusion success after rat embolic stroke

N Henninger, J Bouley, BT Bråtane, B Bastan… - Experimental …, 2009 - Elsevier
BACKGROUND AND PURPOSE: Laser Doppler flowmetry (LDF) is increasingly used to
assess adequate occlusion after embolic stroke (ES) in rats. METHODS: Employing LDF …

[HTML][HTML] Validity of laser doppler flowmetry in predicting outcome in murine intraluminal middle cerebral artery occlusion stroke

VS Hedna, S Ansari, S Shahjouei, PY Cai… - Journal of vascular …, 2015 - ncbi.nlm.nih.gov
Background Laser Doppler flowmetry (LDF) can reliably reflect brain perfusion in
experimental stroke by monitoring both the degree and the duration of relative regional …