The role of inflammatory mediators in epilepsy: focus on developmental and epileptic encephalopathies and therapeutic implications
A Orsini, T Foiadelli, G Costagliola, A Michev… - Epilepsy Research, 2021 - Elsevier
In recent years, there has been an increasing interest in the potential involvement of
neuroinflammation in the pathogenesis of epilepsy. Specifically, the role of innate immunity …
neuroinflammation in the pathogenesis of epilepsy. Specifically, the role of innate immunity …
[HTML][HTML] Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies
W Li, J Wu, Y Zeng, W Zheng - Frontiers in Immunology, 2023 - frontiersin.org
Epilepsy is a group of enduring neurological disorder characterized by spontaneous and
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …
Experimental studies in epilepsy: immunologic and inflammatory mechanisms
A Legido, CD Katsetos - Seminars in pediatric neurology, 2014 - Elsevier
In this article, we review the literature based on experimental studies lending credence to a
relationship between epilepsy and immune-mediated mechanisms linked to central nervous …
relationship between epilepsy and immune-mediated mechanisms linked to central nervous …
Neuroinflammatory pathways as treatment targets and biomarker candidates in epilepsy: emerging evidence from preclinical and clinical studies
EA van Vliet, E Aronica, A Vezzani… - Neuropathology and …, 2018 - Wiley Online Library
Accumulating evidence indicates an important pathophysiological role of brain inflammation
in epilepsy. In this review, we will provide an update of specific inflammatory pathways that …
in epilepsy. In this review, we will provide an update of specific inflammatory pathways that …
Does brain inflammation mediate pathological outcomes in epilepsy?
Inflammation in the central nervous system (CNS) is associated with epilepsy and is
characterized by the increased levels of a complex set of soluble molecules and their …
characterized by the increased levels of a complex set of soluble molecules and their …
Neuroinflammatory mediators in acquired epilepsy: an update
Epilepsy is a group of chronic neurological disorders that have diverse etiologies but are
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …
The role of inflammation in epilepsy
Epilepsy is the third most common chronic brain disorder, and is characterized by an
enduring predisposition to generate seizures. Despite progress in pharmacological and …
enduring predisposition to generate seizures. Despite progress in pharmacological and …
Immunity and inflammation in epilepsy
A Vezzani, B Lang, E Aronica - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
This review reports the available evidence on the activation of the innate and adaptive
branches of the immune system and the related inflammatory processes in epileptic …
branches of the immune system and the related inflammatory processes in epileptic …
Chemokines as new inflammatory players in the pathogenesis of epilepsy
C Cerri, M Caleo, Y Bozzi - Epilepsy Research, 2017 - Elsevier
A large series of clinical and experimental studies supports a link between inflammation and
epilepsy, indicating that inflammatory processes within the brain are important contributors …
epilepsy, indicating that inflammatory processes within the brain are important contributors …
Role of inflammatory mediators in the pathogenesis of epilepsy
T Shimada, T Takemiya, H Sugiura… - Mediators of …, 2014 - Wiley Online Library
Epilepsy is one of the most common chronic brain disorders worldwide, affecting 1% of
people across different ages and backgrounds. Epilepsy is defined as the sporadic …
people across different ages and backgrounds. Epilepsy is defined as the sporadic …