[HTML][HTML] The origin and evolution of the diosgenin biosynthetic pathway in yam

J Cheng, J Chen, X Liu, X Li, W Zhang, Z Dai, L Lu… - Plant …, 2021 - cell.com
Diosgenin, mainly produced by Dioscorea species, is a traditional precursor of most
hormonal drugs in the pharmaceutical industry. The mechanisms that underlie the origin and …

The genome of Dioscorea zingiberensis sheds light on the biosynthesis, origin and evolution of the medicinally important diosgenin saponins

Y Li, C Tan, Z Li, J Guo, S Li, X Chen… - Horticulture …, 2022 - academic.oup.com
Diosgenin saponins isolated from Dioscorea species such as D. zingiberensis exhibit a
broad spectrum of pharmacological activities. Diosgenin, the aglycone of diosgenin …

[HTML][HTML] Comparative Transcriptome Analysis Identifies Putative Genes Involved in Dioscin Biosynthesis in Dioscorea zingiberensis

J Li, Q Liang, C Li, M Liu, Y Zhang - Molecules, 2018 - mdpi.com
Dioscorea zingiberensis is a perennial herb native to China. The rhizome of D. zingiberensis
has long been used as a traditional Chinese medicine to treat rheumatic arthritis. Dioscin is …

Biotechnological strategies for the sustainable production of diosgenin from Dioscorea spp.

R Nazir, V Kumar, S Gupta, P Dwivedi… - Applied Microbiology …, 2021 - Springer
Diosgenin is a plant-derived secondary metabolite mainly present in the members of the
plant family Dioscoreaceae. It is a pharmaceutically important compound because of its anti …

Production of diosgenin from Dioscorea zingiberensis tubers through enzymatic saccharification and microbial transformation

YL Zhu, W Huang, JR Ni, W Liu, H Li - Applied microbiology and …, 2010 - Springer
In order to develop a clean and effective approach for producing the valuable drug
diosgenin from Dioscorea zingiberensis tubers, two successive processes, enzymatic …

[HTML][HTML] Comparative Transcriptome Analysis Identifies Genes Involved in Diosgenin Biosynthesis in Trigonella foenum-graecum L.

C Zhou, X Li, Z Zhou, C Li, Y Zhang - Molecules, 2019 - mdpi.com
Trigonella foenum-graecum L.(fenugreek) is a valuable resource of producing diosgenin
which serves as a substrate for synthesizing more than two hundred kinds of steroidal drugs …

[HTML][HTML] Comparative analysis of diosgenin in Dioscorea species and related medicinal plants by UPLC-DAD-MS

T Yi, LL Fan, HL Chen, GY Zhu, HM Suen, YN Tang… - BMC biochemistry, 2014 - Springer
Background Dioscorea is a genus of flowering plants, and some Dioscorea species are
known and used as a source for the steroidal sapogenin diosgenin. To screen potential …

New insights into diosgenin biosynthesis pathway and its regulation in Trigonella foenum‐graecum L.

M Mohammadi, T Mashayekh… - Phytochemical …, 2020 - Wiley Online Library
Introduction Throughout history, thousands of medicinal and aromatic plants have been
widely utilised by people worldwide. Owing to them possessing of valuable compounds with …

Isolation and characterization of diosgenin from in vitro cultured tissues of Helicteres isora L

HA Deshpande, SR Bhalsing - Physiology and Molecular Biology of Plants, 2014 - Springer
The objective of the present study was to isolate, characterize, quantify and compare the
accumulation of bioactive secondary metabolite—diosgenin from in vitro cultured cells of …

[HTML][HTML] Weighted Gene Co-expression Network Analysis of the Dioscin Rich Medicinal Plant Dioscorea nipponica

W Sun, B Wang, J Yang, W Wang, A Liu… - Frontiers in plant …, 2017 - frontiersin.org
Dioscorea contains critically important species which can be used as staple foods or
sources of bioactive substances, including Dioscorea nipponica, which has been used to …