Oral delivery of natural active small molecules by polymeric nanoparticles for the treatment of inflammatory bowel diseases

M Zu, Y Ma, B Cannup, D Xie, Y Jung, J Zhang… - Advanced Drug Delivery …, 2021 - Elsevier
The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

Nanoparticle-mediated drug delivery systems for the treatment of IBD: current perspectives

C Yang, D Merlin - International journal of nanomedicine, 2019 - Taylor & Francis
Inflammatory bowel disease (IBD), which mainly consists of Crohn's disease and ulcerative
colitis, is a chronic and relapsing inflammatory condition of the gastrointestinal tract. The …

[HTML][HTML] Biodegradable polymeric nanoparticles loaded with flavonoids: A promising therapy for inflammatory bowel disease

M Li, Y Liu, B Weigmann - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a group of disorders that cause chronic non-specific
inflammation in the gastrointestinal (GI) tract, primarily affecting the ileum and colon. The …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Current strategies and potential prospects of nanomedicine-mediated therapy in inflammatory bowel disease

F Chen, Q Liu, Y Xiong, L Xu - International journal of …, 2021 - Taylor & Francis
Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are highly
debilitating. IBDs are associated with the imbalance of inflammatory mediators within the …

[HTML][HTML] Natural product-based nanomedicine in treatment of inflammatory bowel disease

T Khare, SS Palakurthi, BM Shah, S Palakurthi… - International journal of …, 2020 - mdpi.com
Many synthetic drugs and monoclonal antibodies are currently in use to treat Inflammatory
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …

[HTML][HTML] Medicinal plant-based drug delivery system for inflammatory bowel disease

N Li, M Wang, Z Lyu, K Shan, Z Chen, B Chen… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic recurrent intestinal disease. The incidence
rate of IBD is increasing year by year, which seriously endangers human health worldwide …

Nanoparticle-based oral drug delivery systems targeting the colon for treatment of ulcerative colitis

M Zhang, D Merlin - Inflammatory bowel diseases, 2018 - academic.oup.com
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …

[HTML][HTML] Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: selective targeting to diseased versus healthy tissue

S Hua, E Marks, JJ Schneider, S Keely - … : nanotechnology, biology and …, 2015 - Elsevier
Colon targeted drug delivery is an active area of research for local diseases affecting the
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …

Natural proteins and polysaccharides in the development of micro/nano delivery systems for the treatment of inflammatory bowel disease

BM Shah, SS Palakurthi, T Khare, S Khare… - International journal of …, 2020 - Elsevier
Treatments for inflammatory bowel disease (IBD) are typically immunosuppressive. Despite
a range of treatment options, limited efficacy, systemic toxicities like bone marrow …