Interleukin-1β in peripheral monocytes is associated with seizure frequency in pediatric drug-resistant epilepsy
G Yamanaka, T Takamatsu, S Morichi… - Journal of …, 2021 - Elsevier
In this study, we assessed circulating immune cells and plasma cytokine levels in 15
pediatric patients with drug-resistant epilepsy (DRE). DRE patients had a significantly higher …
pediatric patients with drug-resistant epilepsy (DRE). DRE patients had a significantly higher …
[HTML][HTML] Increased production of inflammatory cytokines by circulating monocytes in mesial temporal lobe epilepsy: A possible role in drug resistance
C Milano, M Montali, S Barachini, IS Burzi… - Journal of …, 2024 - Elsevier
We analyzed peripheral blood mononuclear cells (PBMCs) and serum inflammatory
biomarkers in patients with mesial temporal lobe epilepsy (drug-resistant–DR, vs. drug …
biomarkers in patients with mesial temporal lobe epilepsy (drug-resistant–DR, vs. drug …
Cytokine production in blood mononuclear cells from epileptic patients
R Pacifici, L Paris, S Di Carlo, A Bacosi, S Pichini… - …, 1995 - Wiley Online Library
Although convulsive disorders have been associated with immune abnormalities, little is
known about cytokine production in epileptic patients. We evaluated the concentrations of …
known about cytokine production in epileptic patients. We evaluated the concentrations of …
The balance of inhibitory and excitatory cytokines is differently regulated in vivo and in vitro among therapy resistant epilepsy patients
J Hulkkonen, E Koskikallio, S Rainesalo, T Keränen… - Epilepsy research, 2004 - Elsevier
Purpose: Excessive neuronal activity and seizures directly stimulate cytokine expression. In
this study we investigated cytokine production in circulating blood and peripheral blood …
this study we investigated cytokine production in circulating blood and peripheral blood …
[HTML][HTML] Temporal lobe epilepsy: Evaluation of central and systemic immune-inflammatory features associated with drug resistance.
Neuroinflammation is probably one of the factors involved in drug resistance in people with
epilepsy. Finding peripheral markers reflecting the intensity of neuroinflammation could be …
epilepsy. Finding peripheral markers reflecting the intensity of neuroinflammation could be …
Do cytokines have any role in epilepsy?
S Sinha, SA Patil, V Jayalekshmy, P Satishchandra - Epilepsy Research, 2008 - Elsevier
OBJECTIVE: We analyzed cytokines levels in patients with epilepsy and new onset seizure
and correlated it various parameters. MATERIALS AND METHODS: After obtaining consent …
and correlated it various parameters. MATERIALS AND METHODS: After obtaining consent …
Increased frequency of proinflammatory CD4 T cells and pathological levels of serum neurofilament light chain in adult drug‐resistant epilepsy
O Ouédraogo, RM Rébillard, H Jamann… - …, 2021 - Wiley Online Library
Objective Adult drug‐resistant epilepsy (DRE) is associated with significant morbidity.
Infiltration of immune cells is observed in DRE epileptic foci; however, the relation between …
Infiltration of immune cells is observed in DRE epileptic foci; however, the relation between …
NK and CD4+ T cell changes in blood after seizures in temporal lobe epilepsy
S Bauer, M Köller, S Cepok, A Todorova-Rudolph… - Experimental …, 2008 - Elsevier
Immunological phenomena may affect the course of focal epilepsy. We analyzed
prospectively the pre-and postictal distribution of leukocyte subsets in epileptic patients …
prospectively the pre-and postictal distribution of leukocyte subsets in epileptic patients …
[HTML][HTML] Increased interleukin-6 and high-sensitivity C-reactive protein levels in pediatric epilepsy patients with frequent, refractory generalized motor seizures
N Ishikawa, Y Kobayashi, Y Fujii, M Kobayashi - Seizure, 2015 - Elsevier
Purpose Recently, it was found that chronic inflammation contributes to the pathomechanism
of diverse chronic diseases in various organs. There is accumulating evidence that …
of diverse chronic diseases in various organs. There is accumulating evidence that …
Interleukin-6 levels are increased in temporal lobe epilepsy but not in extra-temporal lobe epilepsy
S Liimatainen, M Fallah, E Kharazmi, M Peltola… - Journal of …, 2009 - Springer
Previous studies have reported activation of inflammatory cytokines in seizures, but clinical
characteristics of epilepsy associated with cytokine activation have not been well …
characteristics of epilepsy associated with cytokine activation have not been well …