Currently approved replication-competent and inactivated vaccines are limited by excessive
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …

Despite the undeniable success of vaccination programs in preventing diseases, effective
vaccines against several life-threatening infectious pathogens such as human …

Although vaccines have been the primary defense against widespread infectious disease for
decades, there is a critical need for improvement to combat complex and variable diseases …

Subunit vaccines use delivery platforms to present minimal antigenic components for
immunization. The benefits of such systems include multivalency, self‐adjuvanting …

Self-assembling peptides and peptide derivatives have received significant interest for
several biomedical applications, including tissue engineering, wound healing, cell delivery …

Several different self-assembling peptide systems that form nanofibers have been
investigated as vaccine platforms, but design principles for adjusting the character of the …

Biomaterials created from supramolecular peptides, proteins, and their derivatives have
been receiving increasing interest for both immunological applications, such as vaccines …

Supramolecular materials composed of proteins and peptides have been receiving
considerable attention toward a range of diseases and conditions from vaccines to drug …

To be optimally effective, peptide-based vaccines need to be administered with adjuvants.
Many currently available adjuvants are toxic, not biodegradable; they invariably invoke …

A supramolecular peptide vaccine system was designed in which epitope-bearing peptides
self-assemble into elongated nanofibers composed almost entirely of α-helical structure. The …