Normal physiologic function of organs requires a circulation of interstitial fluid to deliver
nutrients and clear cellular waste products. Lymphatic vessels serve as collectors of this fluid …

The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

First described in 2012, the glymphatic system is responsible for maintaining homeostasis
within the central nervous system, including nutrient delivery, waste clearance, and …

New Findings What is the topic of this review? In this symposium report, we review the
glymphatic clearance from the brain. What advances does it highlight? Evaluation of the …

The brain's high bioenergetic state is paralleled by high metabolic waste production.
Authentic lymphatic vasculature is lacking in brain parenchyma. Cerebrospinal fluid (CSF) …

The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in
recent years, highlighted that fluid is directionally transported within the central nervous …

Throughout the body, lymphatic fluid movement supports critical functions including
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …

The glymphatic hypothesis proposes a mechanism for extravascular transport into and out of
the brain of hydrophilic solutes unable to cross the blood–brain barrier. It suggests that there …

The glymphatic system and meningeal lymphatics have recently been characterized.
Glymphatic system is a glia-dependent system of perivascular channels, and it plays an …

In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …