The potential of Akkermansia muciniphila in inflammatory bowel disease

T Zhang, X Ji, G Lu, F Zhang - Applied microbiology and biotechnology, 2021 - Springer
Akkermansia muciniphila is a next-generation probiotic with significant application
prospects. The role of A. muciniphila in metabolic diseases and tumor immunotherapy has …

Akkermansia muciniphila is a promising probiotic

T Zhang, Q Li, L Cheng, H Buch… - Microbial …, 2019 - Wiley Online Library
Summary Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the
mucosal layer, is considered to be a promising candidate as probiotics. A. muciniphila is …

[HTML][HTML] The role of Akkermansia muciniphila in inflammatory bowel disease: Current knowledge and perspectives

M Zheng, R Han, Y Yuan, Y Xing, W Zhang… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, is a chronic
relapsing gastrointestinal inflammatory disease mediated by dysregulated immune …

Recent findings in Akkermansia muciniphila-regulated metabolism and its role in intestinal diseases

MJ Liu, JY Yang, ZH Yan, S Hu, JQ Li, ZX Xu, YP Jian - Clinical Nutrition, 2022 - Elsevier
The mammalian gastrointestinal tract is colonized with a majority of gut microbes, affecting
host metabolism and homeostasis. Gut microbiota plays a vital role in nutrient exchange …

Alterations of Akkermansia muciniphila in the inflammatory bowel disease patients with washed microbiota transplantation

T Zhang, P Li, X Wu, G Lu, C Marcella, X Ji, G Ji… - Applied microbiology …, 2020 - Springer
Akkermansia muciniphila is a promising probiotic in the gut. This study aimed to determine
the presence and abundance of Akkermansia in patients with inflammatory bowel disease …

[HTML][HTML] Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes

VF Rodrigues, J Elias-Oliveira, ÍS Pereira… - Frontiers in …, 2022 - frontiersin.org
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

[HTML][HTML] Role of Akkermansia in Human Diseases: From Causation to Therapeutic Properties

A Pellegrino, G Coppola, F Santopaolo, A Gasbarrini… - Nutrients, 2023 - mdpi.com
The gut microbiota plays a critical role in the modulation of host metabolism and immune
response, and its impairment has been implicated in many gastrointestinal and …

[HTML][HTML] Strain-Specific Anti-inflammatory Properties of Two Akkermansia muciniphila Strains on Chronic Colitis in Mice

R Zhai, X Xue, L Zhang, X Yang, L Zhao… - Frontiers in cellular and …, 2019 - frontiersin.org
Akkermansia muciniphila is potential probiotic in that its type strain ATCC BAA-835 has
beneficial effects upon obesity and diabetes. However, whether A. muciniphila can improve …

A review of a potential and promising probiotic candidate—Akkermansia muciniphila

D Cheng, MZ Xie - Journal of Applied Microbiology, 2021 - academic.oup.com
Akkermansia muciniphila, a common colonizer in the intestinal mucus layer of humans, has
gradually been considered as promising candidate for the next‐generation probiotic, given …

Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

PD Cani, C Depommier, M Derrien, A Everard… - Nature Reviews …, 2022 - nature.com
Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …