[HTML][HTML] Towards a treatment for neuroinflammation in epilepsy: interleukin-1 receptor antagonist, anakinra, as a potential treatment in intractable epilepsy
G Yamanaka, Y Ishida, K Kanou, S Suzuki… - International Journal of …, 2021 - mdpi.com
Febrile Infection-Related Epilepsy Syndrome (FIRES) is a unique catastrophic epilepsy
syndrome, and the development of drug-resistant epilepsy (DRE) is inevitable. Recently …
syndrome, and the development of drug-resistant epilepsy (DRE) is inevitable. Recently …
Therapeutic effect of Anakinra in the relapsing chronic phase of febrile infection–related epilepsy syndrome
R Dilena, E Mauri, E Aronica, P Bernasconi… - Epilepsia …, 2019 - Wiley Online Library
Febrile infection–related epilepsy syndrome (FIRES) is a severe epileptic encephalopathy
with presumed inflammatory origin and lacking effective treatments. Anakinra is the human …
with presumed inflammatory origin and lacking effective treatments. Anakinra is the human …
Febrile infection‐related epilepsy syndrome treated with anakinra
DL Kenney‐Jung, A Vezzani, RJ Kahoud… - Annals of …, 2016 - Wiley Online Library
Febrile infection‐related epilepsy syndrome (FIRES) is a devastating epileptic
encephalopathy with limited treatment options and an unclear etiology. Anakinra is a …
encephalopathy with limited treatment options and an unclear etiology. Anakinra is a …
[PDF][PDF] Intractable epilepsy (IE) and responses to anakinra, a human recombinant IL-1 receptor agonist
H Jyonouchi, L Geng - J Clin Cell Immunol, 2016 - researchgate.net
Patients with intractable seizures (IE) who failed to respond currently available treatment
measures are clinically challenging, causing significant morbidity and even mortality. Better …
measures are clinically challenging, causing significant morbidity and even mortality. Better …
[HTML][HTML] An in vitro model of drug-resistant seizures for selecting clinically effective antiseizure medications in Febrile Infection-Related Epilepsy Syndrome
M Cerovic, M Di Nunzio, I Craparotta… - Frontiers in …, 2023 - frontiersin.org
Introduction FIRES is a rare epileptic encephalopathy induced by acute unremitting seizures
that occur suddenly in healthy children or young adults after a febrile illness in the preceding …
that occur suddenly in healthy children or young adults after a febrile illness in the preceding …
Anakinra usage in febrile infection related epilepsy syndrome: an international cohort
YC Lai, E Muscal, E Wells, N Shukla… - Annals of clinical …, 2020 - Wiley Online Library
Febrile‐infection related epilepsy syndrome (FIRES) is a devastating neurological condition
characterized by a febrile illness preceding new onset refractory status epilepticus (NORSE) …
characterized by a febrile illness preceding new onset refractory status epilepticus (NORSE) …
Functional deficiency in endogenous interleukin‐1 receptor antagonist in patients with febrile infection‐related epilepsy syndrome
BDS Clarkson, RG LaFrance‐Corey… - Annals of …, 2019 - Wiley Online Library
Objective We recently reported successful treatment of a child with febrile infection‐related
epilepsy syndrome (FIRES), a subtype of new onset refractory status epilepticus, with the …
epilepsy syndrome (FIRES), a subtype of new onset refractory status epilepticus, with the …
[HTML][HTML] Fighting autoinflammation in FIRES: the role of interleukins and early immunomodulation
M Perulli, G Cicala, I Turrini, E Musto… - Epilepsy & Behavior …, 2022 - Elsevier
Febrile infection-related epilepsy syndrome (FIRES) is a challenging condition with
unfavorable outcome in most cases. Preliminary evidence suggests that some interleukins …
unfavorable outcome in most cases. Preliminary evidence suggests that some interleukins …
Interleukin-6 blockade with tocilizumab in anakinra-refractory febrile infection-related epilepsy syndrome (FIRES)
CM Stredny, S Case, AJ Sansevere… - Child neurology …, 2020 - journals.sagepub.com
Febrile infection-related epilepsy syndrome (FIRES) is characterized by new onset refractory
status epilepticus in a previously healthy child that is associated with poor cognitive …
status epilepticus in a previously healthy child that is associated with poor cognitive …
[HTML][HTML] Febrile infection-related epilepsy syndrome (FIRES) treated successfully with anakinra in A 21-year-old woman
C Westbrook, T Subramaniam… - … : official publication of …, 2019 - ncbi.nlm.nih.gov
Discussion: Here we report a second case of super-refractory status epilepticus due to
FIRES responding to anakinra, and the first such case in an adult patient. Anakinra was well …
FIRES responding to anakinra, and the first such case in an adult patient. Anakinra was well …
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