Familial hypercholesterolemia and cardiovascular disease in older individuals

ER Coutinho, MH Miname, VZ Rocha, MS Bittencourt… - Atherosclerosis, 2021 - Elsevier
Background and aims Familial hypercholesterolemia (FH) is characterized by high LDL-
cholesterol (LDL-C) and early atherosclerotic cardiovascular disease (ASCVD). With a lipid …

[HTML][HTML] Familial Hypercholesterolemia in the Elderly: An Analysis of Clinical Profile and Atherosclerotic Cardiovascular Disease Burden from the Hellas-FH Registry

C Antza, CV Rizos, V Kotsis, G Liamis, I Skoumas… - Biomedicines, 2024 - mdpi.com
Background: Familial hypercholesterolemia (FH) carries a high risk of atherosclerotic
cardiovascular disease (ASCVD). As the population ages, the age-related influence on …

Cardiovascular disease onset in old people with severe hypercholesterolemia

ER Coutinho, MH Miname, VZ Rocha, MS Bittencourt… - Atherosclerosis, 2023 - Elsevier
Background and aims Familial hypercholesterolemia (FH) variants are associated with
higher atherosclerotic cardiovascular disease risk (ASCVD) even when compared with other …

Prevalence and patient characteristics of familial hypercholesterolemia in a Chinese population aged 35–75 years: results from China PEACE Million Persons Project

H Teng, Y Gao, C Wu, H Zhang, X Zheng, J Lu, Y Li… - Atherosclerosis, 2022 - Elsevier
Background and aims Familial hypercholesterolemia (FH) is a genetic disorder with a high
burden of arteriosclerotic cardiovascular disease. The prevalence of heterozygous FH is …

Long-term risk of atherosclerotic cardiovascular disease in US adults with the familial hypercholesterolemia phenotype

AM Perak, H Ning, SD De Ferranti, HC Gooding… - Circulation, 2016 - Am Heart Assoc
Background: Heterozygous familial hypercholesterolemia (FH) affects up to 1 in 200
individuals in the United States, but atherosclerotic cardiovascular disease (ASCVD) …

A retrospective study of people with familial hypercholesterolaemia in a Belgian lipid clinic

V Ide, D De Cock, S Pazmino… - Acta …, 2024 - Taylor & Francis
Background Familial hypercholesterolaemia (FH) is a genetic disease characterised by
hypercholesterolaemia and premature cardiovascular events. Early diagnosis and treatment …

Familial hypercholesterolemia in a healthy elderly population

P Lacaze, R Sebra, M Riaz, AJ Hooper… - Circulation: Genomic …, 2020 - Am Heart Assoc
Heterozygous familial hypercholesterolemia (FH) is an autosomal codominant genetic
condition characterized by elevated LDL (low-density lipoprotein) cholesterol and increased …

Genetic diagnosis of familial hypercholesterolemia is associated with a premature and high coronary heart disease risk

F Séguro, JP Rabès, D Taraszkiewicz… - Clinical …, 2018 - Wiley Online Library
Background Familial hypercholesterolemia (FH) is a common autosomal dominant disease
associated with premature coronary heart disease (CHD). Studies tend to show that patients …

Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol

Y Zhang, JS Dron, BK Bellows, AV Khera, J Liu… - JAMA …, 2024 - jamanetwork.com
Importance Familial hypercholesterolemia (FH) is a genetic disorder that often results in
severely high low-density lipoprotein cholesterol (LDL-C) and high risk of premature …

Patients with familial hypercholesterolaemia are characterized by presence of cardiovascular disease at the time of death

HW Krogh, L Mundal, KB Holven… - European heart …, 2016 - academic.oup.com
Aims Untreated familial hypercholesterolaemia (FH) increases the risk of premature
atherosclerosis and cardiovascular disease (CVD). This study investigated the presence of …