Punicalagin, a major ellagitannin isolated from pomegranate, is proved to have various
pharmacological activities with an undefined therapy mechanism. The objective of this …

Inflammatory responses in the blood vessel play a pivotal role in the pathogenesis of
atherosclerosis. Eupatilin, a flavone derived from Artemisia princepsPampanini, has various …

Atherosclerosis may lead to cardiovascular diseases (CVD), which are the primary cause of
death globally. In addition to conventional therapeutics for CVD, use of nutraceuticals that …

Paeonol (2′-hydroxy-4′-methoxyacetophenone), the main active compound of the radix of
Paeonia suffruticosa, has been reported to have a beneficial effect in prevention and …

Objective Niclosamide is known to have anti-cancer and anti-inflammatory activities;
however, its therapeutic mechanism has not been defined. In this study, to explain the …

Our previous results suggested that ruscogenin inhibited tumor necrosis factorα (TNF-α)–
induced leukocyte adhesion, which correlated with its suppression of intercellular adhesion …

Aim Biochanin A, an isoflavone isolated from red clover, cabbage or alfalfa, has been
reported to have anti-inflammatory activity. However, the effects of biochanin A on vascular …

Abstract Objective To investigate whether Paeotang (10–50 μg/mL) suppresses tumor
necrosis factor α (TNF-α)-induced vascular inflammatory processes in human umbilical vein …

Endothelial cell activation, injury and dysfunction have been regarded as one of the initial
key events in the pathogenesis of atherosclerosis. Lipopolysaccharide (LPS), an important …

Background: The isoflavone puerarin is the most abundant isoflavone-C-glucoside extracted
from the root (radix puerariae) of the plant Pueraria lobata and possesses many biological …