A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …

Purpose: Colitis-associated colorectal cancer (CAC) poses substantial challenges for
effective treatment. Currently, there is a considerable need for the development of orally …

Coacervation via liquid-liquid phase separation provides an excellent opportunity to address
the challenges of designing nanostructured biomaterials with multiple functionalities. Protein …

Probiotic oral delivery has crucial implications in biomedical engineering, but its oral
bioavailability remains unsatisfactory because of the limited survival and colonization of …

A major limitation in the drug treatment of inflammatory bowel disease is the inability to
deliver the drug selectively towards the inflamed tissues. Nanotechnology-based drug …

There has been increasing interest in complex coacervates for deriving and transporting
biomaterials. Complex coacervates are a dense, polyelectrolyte‐rich liquid that results from …

Delivering drugs directly to the inflamed intestinal sites to treat inflammatory bowel disease
(IBD), particularly Crohn's and ulcerative colitis, is highly challenging. Recent advances in …

The incidence and progression of inflammatory bowel disease are closely related to
oxidative stress caused by excessive production of reactive oxygen species (ROS). To …

Inflammatory bowel disease (IBD) is a chronic inflammatory gastrointestinal disorder that
affects more than 1 million individuals in the USA. Local therapy with enema formulations …

One of the major challenges in IBD therapy is targeting delivery of the drug to the specific
site of inflammation. A recent approach to combat this problem is the use of nanoparticulate …