Schizophrenia is a severe, chronic psychiatric disorder that devastates the lives of millions of
people worldwide. The disease is characterized by a constellation of symptoms, ranging …

Over the last fifteen years it has become established that 22q11. 2 deletion syndrome
(22q11DS) is a true genetic risk factor for schizophrenia. Carriers of deletions in …

Schizophrenia is a devastating neurodevelopmental disorder that, despite extensive
research, still poses a considerable challenge to attempts to unravel its heterogeneity, and …

The 22q11 deletion syndrome (22q11DS) is the most common microdeletion syndrome in
humans and presents with a complex and variable psychiatric phenotype. Patients show …

Progress in characterizing and predicting psychotic illness in 22q11. 2DS supports this
identifiable subpopulation as a molecular model with important implications for …

Abstract The 22q11. 2 deletion (22q11DS) is a common chromosomal microdeletion and a
potent risk factor for psychotic illness. Prior studies reported widespread cortical changes in …

The 22q11. 2 Deletion Syndrome has significant impact on brain and behavior, with about
25% of individuals developing schizophrenia. The condition offers a model for prospective …

Schizophrenia has a strong genetic component but the mode of inheritance of the disease is
complex and in all likelihood involves interaction among multiple genes and also possibly …

Rare copy number variants contribute significantly to the risk for schizophrenia, with the
22q11. 2 locus consistently implicated. Individuals with the 22q11. 2 deletion syndrome …

The 22q11. 2 deletion syndrome (22q11DS) is caused by an autosomal dominant
microdeletion of chromosome 22 at the long arm (q) 11.2 band. The 22q11DS is among the …