Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs,
targeted therapeutic drugs have become mainstream cancer treatments. Since the first …

Compared with traditional therapies, targeted therapy has merits in selectivity, efficacy, and
tolerability. Small molecule inhibitors are one of the primary targeted therapies for cancer …

Research on molecular targeted therapy of tumors is booming, and novel targeted therapy
drugs are constantly emerging. Small molecule targeted compounds, novel targeted therapy …

Drug repurposing or repositioning has been well-known to refer to the therapeutic
applications of a drug for another indication other than it was originally approved for …

The discovery and development of small molecule cancer drugs has been revolutionised
over the last decade. Most notably, we have moved from a one-size-fits-all approach that …

A high incidence of cancer has given rise to the development of more anti-tumor drugs. From
2015 to 2020, fifty-six new small-molecule anticancer drugs, divided into ten categories …

Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of
the improvements in the life quality of patients, their effectiveness is compromised by several …

The identification of molecular targets and the growing knowledge of their cellular functions
have led to the development of small molecule inhibitors as a major therapeutic class for …

With unprecedented understanding of molecular events underlying human cancer in this
genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers …

Tumor-associated antigens (TAA) or cancer biomarkers are major targets for cancer
therapies. Antibody-based agents targeting the cancer biomarkers include monoclonal …