[HTML][HTML] Exhaled volatilome analysis as a useful tool to discriminate asthma with other coexisting atopic diseases in women of childbearing age

RA Sola-Martínez, G Lozano-Terol, J Gallego-Jara… - Scientific Reports, 2021 - nature.com
The prevalence of asthma is considerably high among women of childbearing age. Most
asthmatic women also often have other atopic disorders. Therefore, the differentiation …

Metabolomics pilot study to identify volatile organic compound markers of childhood asthma in exhaled breath

F Gahleitner, C Guallar-Hoyas, CS Beardsmore… - Bioanalysis, 2013 - Future Science
Background: In-community non-invasive identification of asthma-specific volatile organic
compounds (VOCs) in exhaled breath presents opportunities to characterize phenotypes …

[HTML][HTML] Volatile organic compounds associated with diagnosis and disease characteristics in asthma–A systematic review

AM Peel, M Wilkinson, A Sinha, YK Loke, SJ Fowler… - Respiratory …, 2020 - Elsevier
Background Metabolomics refers to study of the metabolome, the entire set of metabolites
produced by a biological system. The application of metabolomics to exhaled breath …

[HTML][HTML] Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches

W Checkley, MP Deza, J Klawitter, KM Romero… - Respiratory …, 2016 - Elsevier
Background The diagnosis of asthma in children is challenging and relies on a combination
of clinical factors and biomarkers including methacholine challenge, lung function …

[HTML][HTML] Online breath analysis with SESI/HRMS for metabolic signatures in children with allergic asthma

R Weber, B Streckenbach, L Welti, D Inci… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: There is a need to improve the diagnosis and management of pediatric asthma.
Breath analysis aims to address this by non-invasively assessing altered metabolism and …

Human volatilome analysis using eNose to assess uncontrolled asthma in a clinical setting

M Farraia, J Cavaleiro Rufo, I Paciência… - Allergy, 2020 - Wiley Online Library
Background Analyses of exhaled volatile organic compounds (VOCs) have shown
promising results when distinguishing individuals with asthma. Currently, there are no …

[HTML][HTML] Identification of exhaled volatile organic compounds that characterize asthma phenotypes: A J-VOCSA study

M Suzukawa, K Ohta, M Sugimoto, N Ohshima… - Allergology …, 2024 - Elsevier
Background Asthma is characterized by phenotypes of different clinical, demographic, and
pathological characteristics. Identifying the profile of exhaled volatile organic compounds …

Urinary metabolomic profiling reveals biological pathways and predictive signatures associated with childhood asthma

S Li, J Liu, J Zhou, Y Wang, F Jin, X Chen… - Journal of asthma …, 2020 - Taylor & Francis
Background Despite considerable efforts, the pathogenic mechanisms of asthma are still
incompletely understood, due to its heterogeneous nature. However, metabolomics can offer …

[HTML][HTML] Metabolic phenotypes in asthmatic adults: Relationship with inflammatory and clinical phenotypes and prognostic implications

A Santos, H Pité, C Chaves-Loureiro, SM Rocha… - Metabolites, 2021 - mdpi.com
Bronchial asthma is a chronic disease that affects individuals of all ages. It has a high
prevalence and is associated with high morbidity and considerable levels of mortality …

[HTML][HTML] Defining adult asthma endotypes by clinical features and patterns of volatile organic compounds in exhaled air

N Meyer, JW Dallinga, SJ Nuss, EJC Moonen… - Respiratory …, 2014 - Springer
Background Several classifications of adult asthma patients using cluster analyses based on
clinical and demographic information has resulted in clinical phenotypic clusters that do not …