Depressed β‐adrenergic inotropic responsiveness and intracellular calcium handling abnormalities in Duchenne Muscular Dystrophy patients' induced pluripotent …
LN Mekies, D Regev, B Eisen… - Journal of Cellular …, 2021 - Wiley Online Library
Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is an X‐
linked disease affecting male and rarely adult heterozygous females, resulting in death by …
linked disease affecting male and rarely adult heterozygous females, resulting in death by …
Electrophysiological abnormalities in induced pluripotent stem cell‐derived cardiomyocytes generated from Duchenne muscular dystrophy patients
B Eisen, R Ben Jehuda, AJ Cuttitta… - Journal of Cellular …, 2019 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is an X‐linked progressive muscle degenerative
disease, caused by mutations in the dystrophin gene and resulting in death because of …
disease, caused by mutations in the dystrophin gene and resulting in death because of …
Stem cell–derived cardiomyocytes and beta-adrenergic receptor blockade in Duchenne muscular dystrophy cardiomyopathy
Background Although cardiomyopathy has emerged as a leading cause of death in
Duchenne muscular dystrophy (DMD), limited studies and therapies have emerged for …
Duchenne muscular dystrophy (DMD), limited studies and therapies have emerged for …
[HTML][HTML] Bioenergetic and metabolic impairments in induced pluripotent stem cell-derived cardiomyocytes generated from Duchenne muscular dystrophy patients
L Willi, I Abramovich, J Fernandez-Garcia… - International journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene and
dilated cardiomyopathy (DCM) is a major cause of morbidity and mortality in DMD patients …
dilated cardiomyopathy (DCM) is a major cause of morbidity and mortality in DMD patients …
[HTML][HTML] DMD Pluripotent Stem Cell Derived Cardiac Cells Recapitulate in vitro Human Cardiac Pathophysiology
S Jelinkova, A Vilotic, J Pribyl, F Aimond… - … in bioengineering and …, 2020 - frontiersin.org
Duchenne muscular dystrophy (DMD) is a severe genetic disorder characterized by the lack
of functional dystrophin. DMD is associated with progressive dilated cardiomyopathy …
of functional dystrophin. DMD is associated with progressive dilated cardiomyopathy …
Generation of induced pluripotent stem cells from patients with Duchenne muscular dystrophy and their induction to cardiomyocytes
A Hashimoto, AT Naito, JK Lee… - International Heart …, 2016 - jstage.jst.go.jp
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene which
encodes dystrophin protein. Dystrophin defect affects cardiac muscle as well as skeletal …
encodes dystrophin protein. Dystrophin defect affects cardiac muscle as well as skeletal …
Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene (DMD),
and is characterized by progressive weakness in skeletal and cardiac muscles. Currently …
and is characterized by progressive weakness in skeletal and cardiac muscles. Currently …
[HTML][HTML] Amelioration of intracellular Ca2+ regulation by exon-45 skipping in Duchenne muscular dystrophy-induced pluripotent stem cell-derived cardiomyocytes
M Sato, N Shiba, D Miyazaki, Y Shiba… - Biochemical and …, 2019 - Elsevier
Duchenne muscular dystrophy (DMD) is a devastating muscle disorder caused by frameshift
mutations in the DMD gene. DMD involves cardiac muscle, and the presence of ventricular …
mutations in the DMD gene. DMD involves cardiac muscle, and the presence of ventricular …
[HTML][HTML] The intracellular Ca2+ concentration is elevated in cardiomyocytes differentiated from hiPSCs derived from a Duchenne muscular dystrophy patient
F Tsurumi, S Baba, D Yoshinaga, K Umeda, T Hirata… - PLoS …, 2019 - journals.plos.org
Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular
dystrophy. The major symptoms of this condition are walking difficulties, dyspnea caused by …
dystrophy. The major symptoms of this condition are walking difficulties, dyspnea caused by …
[HTML][HTML] Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells
E Shoji, H Sakurai, T Nishino, T Nakahata, T Heike… - Scientific reports, 2015 - nature.com
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating
disease caused by a dystrophin deficiency. Effective suppression of the primary pathology …
disease caused by a dystrophin deficiency. Effective suppression of the primary pathology …
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