Undisclosed, unmet and neglected challenges in multi-omics studies
Multi-omics approaches have become a reality in both large genomics projects and small
laboratories. However, the multi-omics research community still faces a number of issues …
laboratories. However, the multi-omics research community still faces a number of issues …
[HTML][HTML] Statistical single cell multi-omics integration
M Colomé-Tatché, FJ Theis - Current Opinion in Systems Biology, 2018 - Elsevier
Single cell high throughput genomic measurements are revolutionizing the fields of biology
and medicine, providing a means to tackle biological problems that have thus far been …
and medicine, providing a means to tackle biological problems that have thus far been …
[HTML][HTML] Computational strategies for single-cell multi-omics integration
N Adossa, S Khan, KT Rytkönen, LL Elo - Computational and Structural …, 2021 - Elsevier
Single-cell omics technologies are currently solving biological and medical problems that
earlier have remained elusive, such as discovery of new cell types, cellular differentiation …
earlier have remained elusive, such as discovery of new cell types, cellular differentiation …
[HTML][HTML] The technological landscape and applications of single-cell multi-omics
Single-cell multi-omics technologies and methods characterize cell states and activities by
simultaneously integrating various single-modality omics methods that profile the …
simultaneously integrating various single-modality omics methods that profile the …
[HTML][HTML] State of the field in multi-omics research: from computational needs to data mining and sharing
Multi-omics, variously called integrated omics, pan-omics, and trans-omics, aims to combine
two or more omics data sets to aid in data analysis, visualization and interpretation to …
two or more omics data sets to aid in data analysis, visualization and interpretation to …
Advances in bulk and single-cell multi-omics approaches for systems biology and precision medicine
Y Li, L Ma, D Wu, G Chen - Briefings in Bioinformatics, 2021 - academic.oup.com
Multi-omics allows the systematic understanding of the information flow across different
omics layers, while single omics can mainly reflect one aspect of the biological system. The …
omics layers, while single omics can mainly reflect one aspect of the biological system. The …
Computational methods for single-cell multi-omics integration and alignment
S Stanojevic, Y Li, A Ristivojevic… - Genomics, Proteomics …, 2022 - academic.oup.com
Recently developed technologies to generate single-cell genomic data have made a
revolutionary impact in the field of biology. Multi-omics assays offer even greater …
revolutionary impact in the field of biology. Multi-omics assays offer even greater …
[HTML][HTML] Advances in single-cell omics and multiomics for high-resolution molecular profiling
J Lim, C Park, M Kim, H Kim, J Kim… - Experimental & Molecular …, 2024 - nature.com
Single-cell omics technologies have revolutionized molecular profiling by providing high-
resolution insights into cellular heterogeneity and complexity. Traditional bulk omics …
resolution insights into cellular heterogeneity and complexity. Traditional bulk omics …
[HTML][HTML] Methods and applications for single-cell and spatial multi-omics
K Vandereyken, A Sifrim, B Thienpont… - Nature Reviews Genetics, 2023 - nature.com
The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome
from single cells is transforming our understanding of cell biology in health and disease. In …
from single cells is transforming our understanding of cell biology in health and disease. In …
Applications of multi‐omics analysis in human diseases
Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …