The bidirectional relationship between depression and chronic pain is well-recognized, but
their clinical management remains challenging. Here we characterize the shared risk factors …

Introduction: An apparent clinical relationship between pain and depression has long been
recognized, which makes an enormous impact on the individual health care. At present, the …

Background Chronic pain is highly prevalent and a significant source of disability, yet its
genetic and environmental risk factors are poorly understood. Its relationship with major …

Opinion statement For patients with chronic pain, the experience of pain is intimately linked
with psychologic distress. Epidemiologic studies indicate that depression is a common …

Purpose Depression is the most common psychiatric disorder and the largest contributor to
global disability. The Australian Genetics of Depression study was established to recruit a …

Background Studies suggest that poor physical health might be associated with increased
depression and anxiety recurrence. The objectives of this study were to determine whether …

Background: Emotional disorders are common comorbid affectations that exacerbate the
severity and persistence of chronic pain. Specifically, depressive symptoms can lead to an …

Background: Depression and pain are both burdensome ailments that affect a major
proportion of the population. It is evident that depression and pain frequently coexist, with …

Objective Pain commonly coexists with depression, but its impact on treatment outcomes
has not been well studied. Therefore, we prospectively evaluated the impact of comorbid …

Background Major depression is one of the most disabling health conditions internationally.
In recent years, new generation antidepressant medicines have become very widely …