[HTML][HTML] New insights into the functions of progesterone receptor (PR) isoforms and progesterone signaling

JM Azeez, TR Susmi, V Remadevi… - American journal of …, 2021 - ncbi.nlm.nih.gov
Progesterone, the ovarian steroid hormone, regulates a plentitude of biological processes in
tissues ranging from the brain to bones. Recognizing the role of progesterone and its …

90 YEARS OF PROGESTERONE: Progesterone receptor signaling in the normal breast and its implications for cancer

C Brisken, V Scabia - Journal of molecular endocrinology, 2020 - jme.bioscientifica.com
Progesterone is considered as the pregnancy hormone and acts on many different target
tissues. Progesterone receptor (PR) signaling is important for normal development and the …

Molecular mechanisms underlying progesterone receptor action in breast cancer: Insights into cell proliferation and stem cell regulation

ME Cenciarini, CJ Proietti - Steroids, 2019 - Elsevier
The ovarian steroid hormone progesterone and its nuclear receptor, the Progesterone
Receptor (PR), play an essential role in the regulation of cell proliferation and differentiation …

Molecular determinants of context-dependent progesterone receptor action in breast cancer

CR Hagan, CA Lange - BMC medicine, 2014 - Springer
The ovarian steroid hormone, progesterone, and its nuclear receptor, the progesterone
receptor, are implicated in the progression of breast cancer. Clinical trial data on the effects …

Progesterone receptor signaling mechanisms

SL Grimm, SM Hartig, DP Edwards - Journal of molecular biology, 2016 - Elsevier
Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls
developmental processes and proliferation and differentiation during the reproductive cycle …

Progesterone receptors-animal models and cell signaling in breast cancer Diverse activation pathways for the progesterone receptor-possible implications for breast …

C Lanari, AA Molinolo - Breast Cancer Research, 2002 - Springer
Progesterone and estradiol, and their nuclear receptors, play essential roles in the
physiology of the reproductive tract, the mammary gland and the nervous system. Estrogens …

Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation

GE Dressing, CA Lange - Steroids, 2009 - Elsevier
Multiple laboratories have investigated progesterone receptor (PR) involvement in breast
cancer cell cycle progression. There is now a growing body of evidence demonstrating …

Progesterone action in breast, uterine, and ovarian cancers

CH Diep, AR Daniel, LJ Mauro… - Journal of …, 2015 - jme.bioscientifica.com
Progesterone and progesterone receptors (PRs) are essential for the development and
cyclical regulation of hormone-responsive tissues including the breast and reproductive …

90 years of progesterone: progesterone and progesterone receptors in breast cancer: past, present, future

KB Horwitz, CA Sartorius - Journal of molecular …, 2020 - jme.bioscientifica.com
Progesterone and progesterone receptors (PR) have a storied albeit controversial history in
breast cancers. As endocrine therapies for breast cancer progressed through the twentieth …

Challenges to defining a role for progesterone in breast cancer

CA Lange - steroids, 2008 - Elsevier
Progesterone is an ovarian steroid hormone that is essential for normal breast development
during puberty and in preparation for lactation. The actions of progesterone are primarily …