Single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) technologies have
enhanced the understanding of the molecular pathogenesis of neurodegenerative …

Parkinson's disease (PD) is a chronic and progressive neurodegenerative disease leading
to motor dysfunction and, in some cases, dementia. Transcriptome analysis is one promising …

Neurodegenerative diseases affect millions of people worldwide and there are currently no
cures. Two types of common neurodegenerative diseases are Alzheimer's (AD) and …

The continuously prolonged human lifespan is accompanied by increase in
neurodegenerative diseases incidence, calling for the development of inexpensive blood …

Recent evidence demonstrates the power of RNA sequencing (RNA-Seq) for identifying
valuable and urgently needed blood biomarkers and advancing both early and accurate …

Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The
pathological hallmark of PD is loss of dopaminergic neurons and the presence of …

Parkinson's disease (PD) is a prevalent neurodegenerative disorder where recent evidence
suggests pathogenesis may be mediated by inflammatory processes. The molecular …

Neurodegenerative disorders are typically characterized by late onset progressive damage
to specific (sub) populations of cells of the nervous system that are essential for mobility …

Objective: This study aimed to exploit cellular heterogeneity for revealing mechanisms and
identifying therapeutic targets for Parkinson's disease (PD) via single-cell transcriptomics …

The genetic architecture of Parkinson's disease (PD) is complex and multiple brain cell
subtypes are involved in the neuropathological progression of the disease. Here we aimed …