[图书][B] Human iPSC Derived Ameloblast Organoid Guided by Single-Cell Atlas of Human Tooth Development

A Alghadeer - 2022 - search.proquest.com
Tooth enamel secreted by ameloblasts is the hardest material in the human body, acting as
a shield protecting the teeth. However, the enamel is gradually damaged or partially lost in …

[PDF][PDF] Hajime Ozaki1, Hidetaka Suga1Ε, Mayu Sakakibara1, Mika Soen1, Natsuki Miyake2, Tsutomu Miwata1, Shiori Taga1, 3, Takashi Nagai2, Mayuko Kano1 …

K Muguruma, H Inoue10, H Arima - Scientific Reports, 2022 - nagoya.repo.nii.ac.jp
Results Primed FNDI-specific hiPSCs fail to aggregate and differentiate poorly using
conventional methods. Differentiation of mESCs and hESCs into hypothalamic neurons was …

Leveraging Covalent Modification for Diverse Applications in Antiviral Discovery and Kinase Mechanism Deconvolution

JJ Feng - 2022 - search.proquest.com
Covalent target modification has re-emerged in recent years as a promising modality for
therapeutic development and mechanistic biochemical analysis. Although slightly colored by …

[PDF][PDF] Ο ρόλος της θεραπείας κυτταρικής υποκατάστασης με βλαστικά κύτταρα στο αγγειακό εγκεφαλικό επεισόδιο

Ν Αναγνώστου - 2022 - olympias.lib.uoi.gr
Στόχος αυτής της προσέγγισης είναι η παρουσίαση και η εκμάθηση της θεραπείας κυτταρικής
υποκατάστασης με βλαστικά κύτταρα στο αγγειακό εγκεφαλικό επεισόδιο. Η αυξημένη …

Musashi1 and its short C-terminal variants regulate pluripotency states in embryonic stem cells

Y Chen, H Zhang, J Han, Q Li, Y Chen, G Lin - bioRxiv, 2022 - biorxiv.org
ABSTRACT Musashi1 (MSI1) is a marker for adult stem cells, but little is known for its
expression and function in pluripotent stem cells (PSCs). Here we report that MSI1 is …

AMPK-p38 axis converts human pluripotent stem cells to naïve state

Z Yang, Y Liu, H Xu, J Yamane, A Hotta, W Fujibuchi… - bioRxiv, 2022 - biorxiv.org
Pluripotent stem cells (PSCs) have been reported to exhibit two stages of
pluripotency,'primed'and 'naïve'states. Typical human PSCs (hPSCs) are in the primed state …

Differentiation and Expansion of Human Extra-Embryonic Endoderm Cell Lines from Naïve Pluripotent Stem Cells

M Linneberg-Agerholm, JM Brickman - Human Naïve Pluripotent Stem …, 2022 - Springer
In human, endoderm is induced in two waves, with the first being the extra-embryonic
primitive endoderm (PrE), otherwise known as hypoblast, induced during blastocyst …

Study of X Chromosome Activity Status in Human Naive Pluripotent Stem Cells Using RNA-FISH

K Mahadik, C Rougeulle - Human Naïve Pluripotent Stem Cells, 2022 - Springer
X chromosome activity is a defining attribute of naive pluripotency, with naive pluripotency
being a rare context in which both X chromosomes of females are active. RNA-fluorescence …

[图书][B] Exploring Early Development and Regenerative Medicine Using Crispr/Cas9

N Winblad - 2022 - search.proquest.com
Embryonic stem cells are derived from an embryo and exist in two different states: naive
(before implantation) and primed (after implantation). The embryonic stem cells represent an …

[图书][B] Understanding trophoblast development using human embryonic stem cells

RE Morey - 2022 - search.proquest.com
The human placenta is a transient organ that mediates essential feto-maternal interactions
that are critical for a successful pregnancy. Trophoblast cells are specialized placental …